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NCT Number: NCT07528742

Vagus Nerve Stimulation for Reaction Time

Non-Invasive Vagus Nerve Stimulation will be provided to the participants using a transcutaneous electrical nerve stimulation (TENS) unit, a routine physical therapy intervention by the faculty researcher who is a licensed physical therapist. The electrodes will be clipped to ear over the vagus nerve distribution area. The parameters will be 30 Hz, 250 us, 5 minutes, at tolerance (no pain). Reaction time will test collected pre and post the stimulation using online reaction time testing platform.

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Key information

Conditions

Healthy Subjects (HS)

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy participants over the age of 18
  • did not receive vagus nerve stimulation previously

Exclusion criteria

  • alcohol or drug abuse
  • metal in the skull
  • implanted cardiac or cranial devices
  • Women during 3 trimester of pregnancy

Treatment and study plan

vagus nerve stimulation

Device

Non-Invasive Vagus Nerve Stimulation will be provided to the participants using a transcutaneous electrical nerve stimulation (TENS) unit, a routine physical therapy intervention by the faculty researcher who is a licensed physical therapist. The electrodes will be clipped to ear over the vagus nerve distribution area. The parameters will be 30 Hz, 250 us, 5 minutes, at tolerance (no pain)

Primary outcomes

  1. Reaction time

    Time frame: Baseline and immediately after the intervention.

    Reaction time will test collected pre and post the stimulation using online platform. The subjects will press a key when setting a color change in the computer screen.

Study contacts

Contact information is provided by the study sponsor or research team.

Weiqing Ge Ge, DPT, PhD

CONTACT

[email protected]

330-941-2702

Sponsors and collaborators

Lead sponsor

Youngstown State University

Other

Registry information

Official study title

Enhancing Reaction Time Through Non-Invasive Vagus Nerve Stimulation

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Apr 14, 2026
Registry last updated
Apr 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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