Vaccine Confidence Study Among Historically Marginalized Racial and Ethnic Groups

Achieving optimal vaccination rates is vital for protecting the health and well-being of all individuals. This specific study focuses on the MMR and RSV vaccines in pregnancy and early childhood, which have been shown to reduce RSV and MMR-related illnesses, hospitalizations, and deaths. Efforts to improve vaccination rates have not been equally effective across the entire population; this has resulted in poorer outcomes from interventions for certain populations who are vaccine-hesitant.

This study seeks to understand how to best increase vaccine confidence in marginalized populations. To do this, the investigators will interview parents of children who receive care at Boston Medical Center (BMC), Community Health Workers and other Clinical providers at BMC, leading experts in the fields of vaccine confidence and implementation science, and key public health stakeholders/officials.

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Key information

Conditions

Vaccine Hesitancy Behavior Health Behavior Treatment Adherence and Compliance Treatment Refusal Vaccination Hesitancy Vaccination Refusal Vaccine Refusal

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Boston Medical Center

Boston, Massachusetts, 02118, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Parent and child-

The birthing parent of any age of a child (aged 12-24 months) who receives primary care at Boston Medical Center
A birthing parent who is registered as a patient at Boston Medical Center
The birthing parent must have been pregnant between the months of October and February (RSV season)
The birthing parent must be comfortable completing an interview in English, Spanish, or Haitian Creole.

Clinician

Clinical provider (including Community Health Workers, Physicians, Physician Assistants and Nurse Practitioners) aged 18+ years at Boston Medical Center within Pediatrics, Family Medicine, or OB/GYN. These clinicians will have been involved in past or current successful vaccine-specific Evidence Based Interventions (EBI) beyond BMC and its affiliated Community Health Center (CHC).

EBI Expert

Content experts (aged 18+ years) in the areas of Implementation Science, Vaccine-specific EBIs, and Prenatal genetic counseling

Exclusion criteria

Clinical provider (including Community Health Workers, Physicians, Physician Assistants and Nurse Practitioners) at NON-BMC clinic/Community Health Center
Content experts - NON-Vaccine evidence based interventions (EBIs)

Treatment and study plan

Primary outcomes

Vaccine confidence from the parents' perspective

Time frame: 1 day

Interviews will be conducted with parents and themes will be abstracted that relate to vaccine confidence. Counts of participants for each theme will be reported.
Vaccine confidence from the clinicians' perspective

Time frame: 1 day

Interviews will be conducted with clinicians and themes will be abstracted that relate to vaccine confidence. Counts of participants for each theme will be reported.
Vaccine confidence from the EBI Experts' perspective

Time frame: 1 day

Interviews will be conducted with EBI experts and themes will be abstracted that relate to vaccine confidence. Counts of participants for each theme will be reported.

Sponsors and collaborators

Lead sponsor

Boston Medical Center

Other

Collaborators

Merck Sharp & Dohme LLC

Registry information

Official study title

Examining Underlying Factors and Root Cause of Successful Evidence Based Interventions (EBIs) Among Historically Marginalized Racial and Ethnic Groups Using the Consolidated Framework for Implementation Research (CFIR)

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Oct 15, 2024
Registry last updated: Jul 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed