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NCT Number: NCT06680583

Utilizing of Physiological Parameters Predict the Prognosis of Cirrhotic Patients With Gastrointestinal Bleeding

Can physiological indicators such as quick Sequential Organ Failure Assessment , Shock Index, and its derived indicators such as Modified Shock Index , Age Shock Index and Respiratory Adjusted Shock Index accurately predict the prognosis of cirrhosis patients with gastrointestinal bleeding? To explore the improvement of emergency and critical care patient management.

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Key information

Conditions

Liver Cirrhosis Digestive System Diseases Fibrosis Gastrointestinal Bleeding Gastrointestinal Diseases Gastrointestinal Hemorrhage Hemorrhage Liver Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

Cirrhosis is a common chronic liver disease with gastrointestinal bleeding being one of its complications. Gastrointestinal bleeding is quite common in patients with cirrhosis, but its prognosis is difficult to accurately predict. In current clinical practice, critical care physicians often use physiological indicators to assess the risk level of patients. Among them, the Shock Index and its derived indicators such as the Modified Shock Index, Age Shock Index, and Respiratory Adjusted Shock Index have been widely used in other fields, but their actual value in patients with cirrhosis complicated by gastrointestinal bleeding is not yet clear.

The prognosis of cirrhosis patients with gastrointestinal bleeding affects the quality of life and survival of the patients, thus necessitating the establishment of a reliable prognostic assessment tool to assist critical care physicians in making rapid treatment decisions. The motivation of this study is to explore the application value of Shock Index-related indicators in predicting the prognosis of cirrhosis patients with gastrointestinal bleeding, in order to improve the medical efficiency for this specific group of critically ill patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

cirrhosis with gastrointestinal bleeding -

Exclusion criteria

no complete medical record and trauma patient

-

Treatment and study plan

physical indicators such as shock index relatives

Other

shock index relatives indicators used in the prediction of cirrhosis with gastrointestinal bleeding

Other names: MSI, Age SI, RASI

Primary outcomes

  1. shock index= heart rate / systolic blood pressure normal range:0.5-0.7 Modified shock index = heart rate/mean arterial pressure(MAP) age shock index = SI x age number respiratory adjusted shock index(RASI) = HR/SBP × RR/10. MAP = DP + 1/3(SP - DP)

    Time frame: through study completion, an average of 6 months

    find the shock index relatives indicators in the prognosis prediction of cirrhosis with gastrointestinal bleeding

Study contacts

Contact information is provided by the study sponsor or research team.

Chia-Hsi Chen, Physician

CONTACT

[email protected]

886-5-2756000 ext. 3708

Chung-Jing Wang, professor

CONTACT

[email protected]

886-5-2756000 ext. 3708

Sponsors and collaborators

Lead sponsor

St. Martin De Porress Hospital

Other

Registry information

Official study title

Utilizing of Physiological Parameters And Derived Indices to Predict The Prognosis of Cirrhotic Patients With Gastrointestinal Bleeding

Acronym: SI

Important dates

Study start
2024
Primary completion
2027
Study completion
2027
First posted
Nov 8, 2024
Registry last updated
Mar 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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