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Completed

NCT Number: NCT00980707

Utility of Versican and Hyaluronan Measurement in Induced Sputum as Biomarkers of Asthma

The purpose of this study is to determine the role of versican and hyaluronan measurements in induced sputum as biomarkers of asthma. Enroll 10 subjects with mild persistent asthma who are not receiving treatment with a controller therapy.

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Key information

Conditions

Allergic Asthma

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Associated Scientists to Help Minimize Allergies

Seattle, Washington, 98105, United States

About this study

We will compare spirometry, eNO and sputum measurements of versican and hyaluronan before and after treatment with fluticasone 220 ug/bid.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Allergic asthma defined as a positive methacholine challenge

Exclusion criteria

  • Non-atopic patients

Treatment and study plan

Inhaled corticosteroid (fluticasone)

Drug

inhaled fluticasone 220 ug/bid

Other names: fluticasone

Primary outcomes

  1. Compare hyaluronan and versican in asthmatics versus atopic non-asthmatics.

    Time frame: 1 year

Sponsors and collaborators

Lead sponsor

Associated Scientists to Help Minimize Allergies

Other

Collaborators

  • Benaroya Research Institute
  • GlaxoSmithKline

Registry information

Official study title

Utility of Versican and Hyaluronan Measurement in Induced Sputum as Biomarker of Asthma

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Sep 21, 2009
Registry last updated
Jan 19, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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