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Completed

NCT Number: NCT04248660

Uterine Artery Doppler and 11-14 / 20-22 Weeks of Gestation Pregnancy

Uterine artery doppler measurements will be made at 11-14 weeks and 20-22 weeks of gestation, and the classification of these measurements according to type of delivery; and to investigate the change in the effect of delivery type on uterine artery flows on obstetric outcomes (maternal, fetal, neonatal outcomes).

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Key information

Conditions

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

Kanuni Sultan Süleyman Training and Research Hospital

Istanbul, 33404, Turkey (Türkiye)

About this study

The first and second trimester perinatal examination results performed by the same operator from pregnant women who have applied to the clinic since the first trimester are removed from the ViewPoint 6.0 server and database and their uterine artery doppler values (uterine artery PI and RI values, presence of uterine artery notch), placental location, gestational week of measurement, blood pressures, PAPP-A and hCG MoM values, obstetric results (type of birth, week, weight, ante-postpartum complications), data to be generated from other hospital records will be saved to the base

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Gestational age 11-14. applying to the outpatient clinic at week
  • Single spontaneous pregnancy
  • Having a first pregnancy (primigravid nullipar) or having given birth once (primipar) (first birth by vaginal route or cesarean)
  • Result of previous pregnancy with live birth (term delivery without obstetric complication)
  • No intrauterine growth restriction in the first pregnancy
  • Women who gave birth by cesarean section were not placed due to caesarean indication due to placental location-invasion anomaly, maternal chronic disease (hypertension, diabetes, coronary artery disease, etc.), placental detachment.

Exclusion criteria

  • Multiple pregnancies
  • Pregnancies with assisted reproductive techniques
  • Placental anomaly in previous pregnancy
  • Maternal chronic hypertension, preeclampsia, history of diabetes
  • Pregnant women who smoke
  • The presence of fetal chromosomal or structural anomaly
  • two or more cesarean sections
  • Having undergone non-cesarean surgery (myomectomy, septum or polyp resection ... etc)
  • Presence of uterine structural anomaly

Treatment and study plan

uterine artery doppler measurement

Other

The effect of delivery type on changes in uterine blood flow will be investigated.

Doppler results groups will be defined according to the effect of deviations in uterine blood flow on neonatal and perinatal results.

Primary outcomes

  1. Doppler results of 11-14 weeks of gestation in patients with previous cesarean section

    Time frame: 10 months

    uterine artery doppler values (uterine artery PI , presence of uterine artery notch)

  2. Doppler results of 11-14 weeks of gestation in those who gave birth beforehand

    Time frame: 10 months

    uterine artery doppler values (uterine artery PI , presence of uterine artery notch)

  3. Doppler results of 20-22 weeks of gestation in patients with previous cesarean section

    Time frame: 10 months

    uterine artery doppler values (uterine artery PI , presence of uterine artery notch)

  4. Doppler results of 20-22 weeks of gestation in those who gave birth beforehand

    Time frame: 10 months

    uterine artery doppler values (uterine artery PI , presence of uterine artery notch)

Sponsors and collaborators

Lead sponsor

Kanuni Sultan Suleyman Training and Research Hospital

Other

Registry information

Official study title

Comparison of Uterine Artery Doppler Measurements Performed at 11-14 and 20-22 Weeks of Gestation During Pregnancy According to Delivery Type and Number of Births and Investigation of the Effects on Obstetric Outcomes (Maternal, Fetal, Neonatal Results)

Important dates

Study start
2016
Primary completion
2020
Study completion
2020
First posted
Jan 30, 2020
Registry last updated
Jan 30, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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