Faculty of medicine,Assiut universty,Egypy
Asyut, Asyut Governorate, 2063045, Egypt
Not Yet Recruiting
NCT Number: NCT06623877
Using Renal Elastography Measurements for Evaluation of Glomerulonephritis Patients
All participants will clinically evaluated by history taking, full physical examination including body weight and assessment of fluid status, and blood and urine samples for lab analysis (serum creatinine, urea, sodium, potassium, corrected calcium, phosphorous, estimated glomerular filtration rate(GFR) by Cokcroft equation ((140 - age ) x body weight by Kg/creatinine by µmol )complete urine analysis including microscopic examination of urine , 24 hours urinary protein , haemoglobin level .
All participants will undergo renal shear wave elastography measurements. Values will be obtained from the upper, middle, and lower zones of each kidney. A total of six shear wave elastography measurements will be collected to get mean elastography values (MEVs) of each participant.
Not Yet Recruiting
Trial opening soon.
Get NotifiedKey information
Age range
18 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
About this study
We will collect results of MEV plus blood and urine samples of each participant then data will undergo statistical analysis to compare between MEV of healthy persons and biopcy proven glomerulonephritis patients
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
a-inclusion criteria :
- adult patients aged 18 years old or more
- patients diagnosed as glomerulonephritis ( biopcy proven ) and not started specific tratement in Assiut University Hospitals
b. Exclusion criteria:
- patient with urinary tract obstruction
- patient who has GN and started corticosteroid and/or immunosuppressive drugs
- patient who has congenital anomalies in renal system
Treatment and study plan
renal shear wave elastography
Diagnostic TestRenal shear wave elastography is a non-invasive ultrasound elastography technique that allows measurements of tissue stiffness. It provides real-time measurements of shear wave velocity (SWV) generated with an acoustic impulse, thereby providing quantitative information about tissue elasticity. Harder tissues have been shown to have higher SWV .
Renal shear wave elastography will be done to both groups
Primary outcomes
-
comparisons between the shear wave elastography measurements in GN patients and healthy persons .
Time frame: One year
Sponsors and collaborators
Lead sponsor
Assiut University
Other
Registry information
Important dates
- Study start
- 2024
- Primary completion
- 2025
- Study completion
- 2025
- First posted
- Oct 2, 2024
- Registry last updated
- Oct 2, 2024
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.