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Active, Not Recruiting

NCT Number: NCT06751342

Using Psychophysics Methods to Investigate Sensory Dominance After Cataract Surgery

Using Psychophysics Methods for Quantitative Assessment of Sensory Binocular Imbalance After Cataract Surgery

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

6 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Ophthalmology and Optometry Hospital, Wenzhou

Wenzhou, Zhejiang, 325027, China

About this study

Using binocular phase combination paradigms and binocular rivalry paradigms to quantitatively assess the degree of sensory binocular imbalance in patients following cataract surgery, investigating the relationship between unilateral and bilateral cataracts in children and varying severities of cataracts in adults with respect to sensory ocular dominance, and forecasting the postoperative quality of life for patients.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Ages between 6 and 90 years old, and the individual or legal guardian is capable of understanding and voluntarily signing an informed consent form;
  • No history of ocular trauma or intraocular surgery, no physical or medical treatments have been undergone, and the clinical diagnosis in the medical records is age-related, congenital, or developmental cataract patients;
  • Best-corrected visual acuity in both eyes is greater than 0.8 before the study, fusion ability is normal as checked by Worth's 4-dot test, and at least 1 month has passed since the last surgery;
  • Good communication skills and the ability to understand and grasp the trial;
  • No significant contraindications to surgery found in preoperative systemic and ocular examinations.

Exclusion criteria

  • Patients with traumatic or complex cataracts;
  • Those diagnosed with glaucoma before or after surgery;
  • Individuals with a history of intraocular surgery (such as vitrectomy) or laser treatment;
  • Exclude those with severe ocular comorbidities (including microphthalmia, aphakia, anterior segment dysgenesis, uveitis, optic nerve dysplasia, retinopathy of prematurity, congenital glaucoma, etc.) and severe systemic comorbidities (including syndromes affecting connective tissue function, such as Marfan syndrome, homocystinuria, or Down syndrome, severe birth defects, and epilepsy);
  • Any systemic diseases related to the eyes, such as rheumatic immune diseases;
  • Those with surgical records indicating any severe intraoperative complications during cataract surgery;
  • Individuals who cannot cooperate with the examination.

Treatment and study plan

Primary outcomes

  1. Perceptual Phase

    Time frame: Each subject undergoes a one-time examination, which lasts for about a year. Each subject's participation in this clinical study will take approximately 0.5 hour.

    The perceptual phase when the interocular contrast between the two eyes is 1.

  2. Ocular Dominance Index (ODI)

    Time frame: Each subject undergoes a one-time examination, which lasts for about a year. Each subject's participation in this clinical study will take approximately 0.5 hour.

    The ratio of the total time spent by the observer reporting complete dominance of visual stimuli presented to the dominant or non-dominant eye.

Sponsors and collaborators

Lead sponsor

Wenzhou Medical University

Other

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Dec 27, 2024
Registry last updated
Dec 27, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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