Bispebjerg Hospital, department of anesthesiology
Copenhagen, 2400, Denmark
NCT Number: NCT01840800
Anterior cruciate ligament reconstruction is a routine surgical procedure. Traditional femoral/sciatic block combinations effectively reduce postoperative pain, but results in considerable motor blockade. The investigators aimed to evaluate postoperative pain relief and the degree of motor block with block combinations of femoral nerve (FEM) and obturator [posterior branch] nerve (ONP), versus saphenous nerve (SAPH) and ONP, versus placebo blocks with isotonic saline. All patients received standard patient controlled analgesia with morphine.Randomized, placebo-controlled and double-blinded clinical trial. Following IRB approval, 81 patients were planned to be randomized to one of three USG block combinations: Active FEM+ONP, active SAPH+ONP or no active blocks (sham blocks) Ropivacaine 0.75% was used for all active blocks following induction of general anaesthesia [propofol-remifentanil, laryngeal mask airway]. Primary outcome measure: Localized PACU pain scores (AUC) 0-6 hours postoperatively at rest.
Secondary outcome measures: Opioid consumption, opioid related side effects, PACU time, motor abilities of daily living scores [modified Barthel/100 index], perceived ill health [Short form-8] scores and degree of motor blockade [Jensen- Børglum motor test].
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Copenhagen, 2400, Denmark
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: Area under the curve (AUC) 0-6 hours postoperatively
Numerical rating scale(0-10)
Time frame: 0-6 hours postoperatively
Opioid consumption (PCA pump - mg of morphine)
Time frame: 0-6 hours postoperatively
Nausea (0-3), vomiting (>10 ml)
Time frame: 0-6 hours postoperatively
Minutes in PACU
Time frame: 0-24 hours postoperatively
Modified Barthel/100 index
Time frame: 0-24 hours postoperatively
Short-Form-8
Time frame: 0-6 hours postoperatively
Jensen-Borglum motor test
Jens Borglum Neimann
Other
Ultrasound Guided Nerve Block Combinations for Anterior Cruciate Ligament Reconstruction; Femoral, Saphenous and Obturator (Posterior Branch)Nerves.
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