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Recruiting

NCT Number: NCT07223086

Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity

The purpose of this study is to gather pilot data on the effectiveness of daily disposable tinted contact lenses in reducing photophobia (light sensitivity) following a concussion, with the goal of facilitating the return to work or school.

Recruiting

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Key information

Conditions

Concussion, Mild Brain Concussion Brain Diseases Brain Injuries Brain Injuries, Traumatic Central Nervous System Diseases Contact Lens Craniocerebral Trauma Eye Diseases Head Injuries, Closed Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Photophobia Sensation Disorders Signs and Symptoms Trauma, Nervous System Vision Disorders Wounds and Injuries Wounds, Nonpenetrating

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UAB Eye Care

Birmingham, Alabama, 35294, United States

Location status: Recruiting

Location contact

Candice I Turner, OD

CONTACT

[email protected]

(205)934-0997

Candice I Turner, OD

PRINCIPAL_INVESTIGATOR

Heidi Hernandez, OD

SUB_INVESTIGATOR

Katherine K Weise, OD

CONTACT

[email protected]

(205) 934-6758

Katherine K Weise, OD

SUB_INVESTIGATOR

Mallory Wright, OD

SUB_INVESTIGATOR

Mark Swanson, OD

SUB_INVESTIGATOR

Thom Houston, MD

SUB_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • diagnosed mild traumatic brain injury (concussion)
  • age 18 or older
  • Within 24 months of initial injury
  • experiencing symptoms of photophobia (light sensitivity), increased photophobia since the injury, or no symptoms of photophobia

Exclusion criteria

  • moderate or severe concussion
  • active infection or inflammation that contradicts the use of soft contact lenses
  • subjects unable to safely perform insertion and removal of the contact lenses

Treatment and study plan

Narrow band (tinted) contact lenses

Device

Participants will receive these contacts based on the results of the Utah Photophobia Symptom Impact Scale (survey).

Other names: Altius contact lenses

broad band (clear) contact lenses

Device

Participants will receive these contacts based on the results of the Utah Photophobia Symptom Impact Scale (survey).

Other names: BioTrue One Day, Infuse daily disposable contact lenses, Clariti 1 Day clear contact lenses

Primary outcomes

  1. Number of participants that improved symptoms of light sensitivity with narrow band (tinted) contact lenses

    Time frame: Baseline, 1 week

    Improvement in the Utah Photophobia Symptom Impact Scale version 2 (UPSIS-2) on a scale of 15-60. Anything over 26 is considered significant.

Study contacts

Contact information is provided by the study sponsor or research team.

Candice I Turner, OD

CONTACT

[email protected]

(205)934-0997

Katherine K Weise, OD

CONTACT

[email protected]

(205) 934-6758

Sponsors and collaborators

Lead sponsor

University of Alabama at Birmingham

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Oct 31, 2025
Registry last updated
Jun 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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