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OpenTrials
Completed

NCT Number: NCT03286764

Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility

The investigators hypothesize that spraying peppermint oil containing L-menthol onto the colonic mucosa during colonoscopy will relax smooth muscle allowing better colonic visualization.

Completed

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Key information

Conditions

Enhancement of the ADR During Colonoscopy

Age range

50 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Screening colonoscopy
  • Age 50 years and older
  • Able to give consent

Exclusion criteria

  • No consent obtained or adult lacking capacity to consent
  • Do not reach cecum on colonoscopy
  • Renal impairment (defined as CrCl <30 ml/min)
  • Allergy to study peppermint oil solution
  • History of colon resection
  • Inflammatory bowel disease
  • Known colorectal neoplasia
  • Non-correctable coagulopathy
  • Pregnancy or lactating
  • Prisoners

Treatment and study plan

Peppermint oil

Other

Distilled water

Other

Distilled water spray as a placebo during Colonoscopy

Primary outcomes

  1. Determination of Adenoma Detection Rate during Colonoscopy Procedure

    Time frame: 2 hours

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Important dates

Study start
2016
Primary completion
2019
Study completion
2019
First posted
Sep 18, 2017
Registry last updated
Apr 3, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.