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OpenTrials
Enrolling by Invitation

NCT Number: NCT07653165

Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds

Use of a motorized waterjet to debride wounds to improve healing outcomes.

Enrolling by Invitation

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Key information

Conditions

Chronic Lower Leg Ulcer Cardiovascular Diseases Diabetic Lower Extremity Ulcers Leg Ulcer Pressure Injuries Pressure Ulcer Skin Diseases Skin Ulcer Skin and Connective Tissue Diseases Surgical Wound Surgical Wounds Traumatic Wounds and Injuries Varicose Ulcer Varicose Veins Vascular Diseases Wounds and Injuries

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

West Boca Center for Wound Healing

Coconut Creek, Florida, 33073, United States

About this study

Hydroprep is a powered waterjet of saline solution used to debride, remove and surgically clean an open wound of any type to improve its ability to heal. The device may also be used to prepare a wound prior to application of a tissue product or a skin graft from the patient. Between treatments, the use of a negative pressure suction portable unit will be used to improve the healing outcome of the wound.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Any chronic lower extremity wound greater than 30 days duration.

Exclusion criteria

  • Active infection or previous tissue grafting.

Treatment and study plan

Motion NPWT

Device

Negative Pressure application

Primary outcomes

  1. Percent Area Reduction of Wound Size

    Time frame: 28 days

    PAR reduction

Secondary outcomes

  1. "Graft Ready State"

    Time frame: Within 28 days

    Time to achieve target wound to a Graft-ready status

  2. Number of Negative Pressure Dressing Applications

    Time frame: 28 days

    Actual number of times the NPWT dressing was changed prior to discontinuation

Sponsors and collaborators

Lead sponsor

West Boca Center for Wound Healing

Other

Registry information

Official study title

A Prospective, Open-Label, Single-Arm Clinical Trial Evaluating the Efficacy of Hydroprep Wound Therapy Followed by Motion Negative Pressure Wound Therapy in the Treatment of Chronic Lower Extremity Wounds

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jun 17, 2026
Registry last updated
Jun 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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