Hadassah Ein Kerem
Jerusalem, Israel, 9112100
Location status: Recruiting
Location contact
Benjamin E Reubinoff, Professor
CONTACT
972-2-6776424/5
Shelly E Tannenbaum, MSQA
CONTACT
Recruiting
NCT Number: NCT00801372
Use of Existing Fibroblast Cells to Convert to Induced Pluripotent Stem Cells
Induced pluripotent stem cells potentially may be useful in the future as an unlimited source of cells for transplantation.
The major goal of the project is to develop human iPS cells from existing lines of fibroblasts that were originally donated as clinical grade feeders for the development of clinical grade hESCs. The clinical grade feeders were developed from aborted fetuses, foreskin and umbilical cord.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
The potential to reprogram somatic cells into an embryonic state raises multiple basic research questions related both to the process of reprogramming and the properties of iPS cells. We will use various approaches to study the molecular mechanisms and processes that occur during reprogramming. We will use various experimental systems to characterize and study the properties of the iPS cells, their biology, developmental potential, capability to give rise to functional differentiated progeny etc.
The clinical grade donated feeders used in this project were developed under GMP conditions using animal-free reagents. For potential future clinical applications, the iPS cells will be developed under GMP conditions, using reagents and methods that will be acceptable for clinical applications.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- healthy, older than 18
Exclusion criteria
- non healthy, younger than 18
Study contacts
Contact information is provided by the study sponsor or research team.
Benjamin E Reubinoff, MD PhD
CONTACT
Shelly E. Tannenbaum, MSQA
CONTACT
Sponsors and collaborators
Lead sponsor
Hadassah Medical Organization
Other
Registry information
Important dates
- Study start
- 2008
- Primary completion
- 2030
- Study completion
- 2030
- First posted
- Dec 3, 2008
- Registry last updated
- Mar 19, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.