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OpenTrials
Completed

NCT Number: NCT05282706

Use of Aromatherapy in Conjunction With Physical/Occupational Therapy in an Acute Care Setting

Use of inhaled essential oils to reduce the symptoms of pain or nausea, enabling a patient to have increase participation with PT or OT, thereby minimizing hospitalization-related risks and potentially reducing the length of stay in the hospital.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Bianca Gonzales

San Antonio, Texas, 78253, United States

About this study

The study intervention consists of 3 essential oils: lavender, mandarin and peppermint administered on an inhalation patch affixed in the chest region of the participant gown. The inhalation patch consists of hydrogel cast onto polyester film, supported by non-woven polyester fabric, covered with a polyethylene film. The proprietary foil-backed lamination on the patch is used to provide an occlusive barrier that prevents any essential oil from being absorbed through the skin. The placebo will consist of a comparable sized felt patch with adhesive backing with no essential oil applied.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Inpatients of acute care setting at University Health hospital
  • Provision of a signed and dated informed consent form
  • English or Spanish speaking
  • Male or Female, aged 18 years and older
  • Willing to comply with all study procedures

Exclusion criteria

  • Respiratory disorders, e.g., asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema, lung cancer, cystic fibrosis, pneumonia, pleural effusion
  • Cognitive impairment
  • Unable to communicate
  • Admitted to the closed access unit or to psychiatry
  • Allergic to lavender, mandarin or peppermint oil
  • Diseases that cause olfactory disorders such as: COVID-19, benign growths or polyps, congestion from a cold, sinus infection or allergy flare-up
  • Drugs that may cause loss of the ability to smell e.g., intranasal zinc products, decongestant nose sprays and certain oral drugs such as nifedipine and phenothiazines
  • Pregnant women (self-reported)
  • Prisoner

Treatment and study plan

Lavender Oil

Drug

A hydrogel lavender oil infused aromatherapy patch

Other names: Lavender Aromatherapy Patch

Mandarin Oil

Drug

A hydrogel mandarin oil infused aromatherapy patch

Other names: Mandarin Aromatherapy Patch

Peppermint oil

Drug

A hydrogel peppermint oil infused aromatherapy patch

Other names: Peppermint Aromatherapy Patch

Placebo

Other

A placebo patch containing no aromatherapy oil

Other names: Placebo patch

Primary outcomes

  1. Completion of PT/OT session

    Time frame: 30 minutes

    The number of subjects who successfully completed physical or occupational therapy session

Secondary outcomes

  1. Change in Pain/Nausea Scale

    Time frame: Baseline to post therapy follow-up (30 minutes)

    A scale with ranks the pain or nausea from 0 to 10 with a 0 being no pain or nausea and 10 being the worst pain

Other outcomes

  1. Increase in participation in PT and OT sessions

    Time frame: 30 minutes

    An exploratory measure to compare whether the use of aromatherapy changes the number of participants in PT or OT.

Sponsors and collaborators

Lead sponsor

The University of Texas Health Science Center at San Antonio

Other

Collaborators

  • University Health

Registry information

Official study title

A Placebo-controlled Clinical Trial Investigating the Use of Aromatherapy in Conjunction With Physical/Occupational Therapy in an Acute Care Setting

Important dates

Study start
2022
Primary completion
2025
Study completion
2025
First posted
Mar 16, 2022
Registry last updated
Jun 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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