Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07370428

US-Guided Quadro-Iliac Plane Block for Postoperative Analgesia After Lumbar Instrumentation

Lumbar instrumentation surgery is associated with significant postoperative pain. This study evaluates the analgesic effectiveness of the ultrasound-guided Quadro-Iliac Plane Block in patients undergoing lumbar instrumentation surgery, aiming to assess the efficacy of this newly developed technique for postoperative pain management.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Postoperative Pain Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Perceptual Disorders Postoperative Complications Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bursa City Hospital

Bursa, 16110, Turkey (Türkiye)

Location status: Recruiting

Location contact

Merih Yildiz Eglen, MD

CONTACT

[email protected]

+905059340629

About this study

Lumbar instrumentation surgery is associated with significant postoperative pain, which may reduce patient comfort, delay early mobilization, and increase analgesic requirements. Effective postoperative pain management is essential for enhancing recovery and reducing postoperative morbidity. In this context, regional anesthesia techniques have become an important component of multimodal analgesia strategies.

The Quadro-Iliac Plane Block is a newly described ultrasound-guided regional analgesia technique. This block aims to provide effective analgesia by targeting the relevant branches of the lumbar nerves supplying the surgical area. However, clinical evidence regarding its effectiveness in postoperative analgesia following lumbar instrumentation surgery remains limited.

This study aims to evaluate the postoperative analgesic effectiveness of the ultrasound-guided Quadro-Iliac Plane Block in patients undergoing lumbar instrumentation surgery. The findings of this study are expected to contribute to the assessment of this newly developed technique as a safe and effective option for postoperative pain management in lumbar spine surgery.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Classified as American Society of Anesthesiologists (ASA) physical status I-III
  • Scheduled for elective lumbar instrumentation surgery
  • Surgery performed under general anesthesia
  • Provision of written informed consent

Exclusion criteria

  • Use of anticoagulant or antiplatelet medications
  • Presence of bleeding diathesis or coagulation disorders
  • Known allergy or hypersensitivity to local anesthetics or opioid medications
  • Infection at the planned block site
  • Alcohol or drug dependence
  • Cognitive impairment preventing reliable pain assessment using the NRS
  • Pregnancy or lactation
  • History of previous lumbar spine surgery
  • Diabetes mellitus
  • Renal or hepatic impairment

Treatment and study plan

Quadro-Iliac Plane Block

Procedure

Ultrasound-guided regional anesthesia technique performed between the erector spinae muscle and the quadratus lumborum muscle at the iliac crest level.

Primary outcomes

  1. Postoperative 48-Hour PCA Opioid Consumption

    Time frame: Postoperative 0-8, 8-16, 16-24, 24-48 intervals

    Total amount of opioid delivered by the patient-controlled analgesia (PCA) device during the first 48 hours after surgery, recorded in milligrams (mg).

  2. QoR-15 Recovery Score

    Time frame: Postoperative 24th and 48th hours

    The investigators will use the Turkish version of Quality of Recovery (QoR) / QoR-15 questionairre

    PART A How have you been feeling in the last 24 hours? (0 to 10, where: 0 = none of the time [poor] and 10 = all of the time [excellent])

    Able to breathe easily Been able to enjoy food Feeling rested Have had a good sleep Able to look after personal toilet and hygiene unaided Able to communicate with Getting support from hospital doctors and nurses Able to return to work or usual home activities Feeling comfortable and in control Having a feeling of general well-being

    PART B Have you had any of the following in the last 24 hours? (10 to 0, where: 10 = none of the time [excellent] and 0 = all of the time [poor]) Moderate pain Severe pain Nausea or vomiting Feeling worried or anxious Feeling sad or depressed

Secondary outcomes

  1. Dynamic and static NRS scores

    Time frame: 0, 2, 4, 8, 16, 24, and 48 hours postoperatively

    Numeric Rating Scale (NRS) (0-10) pain scores at rest or movement at predefined postoperative hours

  2. Total rescue analgesic dose

    Time frame: Postoperative 24th and 48th hours

    Despite the use of patient-controlled analgesia (PCA), if the Numeric Rating Scale (NRS) score is ≥4 at any time point, 0.5 mg/kg intravenous meperidine will be administered as rescue analgesia.

    Total amount of meperidin during the first 24 and 48 hours after surgery, recorded in milligrams (mg).

  3. Time of first request for rescue analgesia

    Time frame: Postoperative 48-Hours

    Despite the use of patient-controlled analgesia (PCA), if the Numeric Rating Scale (NRS) score is ≥4 at any time point, 0.5 mg/kg intravenous meperidine will be administered as rescue analgesia.

  4. Length of Hospital Stay

    Time frame: Patients will remain under observation for at least 2 weeks until their postoperative discharge. Follow-up will be completed upon discharge. The length of hospital stay will be recorded (day).

    Length of hospital stay will be defined as the number of days from the end of surgery to hospital discharge.

  5. Block and Opioid-Related Adverse Effects and Complications

    Time frame: Postoperative 48-Hours

    Block- and opioid-related adverse effects and complications, including but not limited to local anesthetic toxicity, hematoma, infection, nerve injury, nausea, vomiting, pruritus, sedation, and respiratory depression, will be recorded

Study contacts

Contact information is provided by the study sponsor or research team.

Merih Yıldız Eglen, MD

CONTACT

[email protected]

+905059340629

Mursel Ekinci, Assoc prof,MD

CONTACT

[email protected]

+905067137596

Sponsors and collaborators

Lead sponsor

Bursa City Hospital

Other Gov

Registry information

Official study title

Evaluation of the Effectiveness of Ultrasound-Guided Quadro-Iliac Plane Block in Postoperative Analgesia Management Following Lumbar Instrumentation Surgery

Acronym: QIPB

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jan 27, 2026
Registry last updated
Mar 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.