Urinary Excretion of Anthocyanins During Long Term Blueberry Feeding

Essentially all of the published data on anthocyanin absorption in humans are from short term studies - a few days or less, most typically 24 h. However human studies demonstrating clinical effects are typically conducted for several weeks or even months. To examine how anthocyanin absorption and metabolism may be affected this study will examine urinary excretion of anthocyanins over one month, followed by a one week washout, and then one more dose of blueberry juice.

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Key information

Conditions

Bioavailability

Age range

20 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Atlantic Food & Horticulture Research Centre

Kentville, Nova Scotia, B4N 1J5, Canada

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Provided written consent (see: Information and Consent Form)
Fluent in English
Complete a confidential medical questionnaire (Appendix 6)
Able and willing to abide by the dietary restrictions as described
Able and willing to abide by the urine collection protocols as described

Exclusion criteria

No written consent
No confidential medical questionnaire
Unable to comply with diet restrictions and other study requirements

Treatment and study plan

Blueberry Juice

Other

Dietary intervention

Other names: Single strength wild blueberry juice, commercially prepared.

Primary outcomes

Anthocyanins and Phase 2 anthocyanin conjugates in urine

Time frame: 5 weeks

Secondary outcomes

White blood cell gene expression at start and end of study

Time frame: 4 weeks

Sponsors and collaborators

Lead sponsor

Atlantic Food and Horticulture Research Center

Other Gov

Registry information

Important dates

Study start: 2012
Primary completion: 2012
Study completion: 2012
First posted: Feb 12, 2013
Registry last updated: Feb 12, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed