Skip to main content
OpenTrials
Completed

NCT Number: NCT05568862

Ureteric Jet Doppler Waveforms in Patients With Spinal Cord Injury

Urinary dysfunction is very common in individuals with spinal cord injury. The urine flowing from the collecting ducts to the renal calyx stretches the calyces. ANS controlled peristaltic contractions originate in the proximal renal pelvis and travel down the ureters, pushing urine from the renal pelvis towards the bladder. The urine bolus delivered from the kidneys through the peristaltic contraction of the ureter creates an image called ureteric jet. Using the Doppler analysis of ureteral jets, previous studies have examined the changes in the ureteric jet pattern in pathological conditions such as the diagnosis of normal ureteral physiology.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Spinal Cord Injuries Central Nervous System Diseases Nervous System Diseases Spinal Cord Diseases Trauma, Nervous System Wounds and Injuries

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Gaziler PMR, Training and Research Hospital, Department of PMR

Ankara, Çankaya, 06100, Turkey (Türkiye)

About this study

This cross-sectional study was conducted at a tertiary rehabilitation center. Eighteen spinal cord injury patients who met the inclusion criteria and 24 healthy volunteers were included in the study. The appearance of üreteric jet form and bladder wall thicknesses were obtained by urinary Doppler ultrasound both in patient and control groups. Detrusor pressure and bladder volume were measured only in patient group during urodynamic assessment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

The case group

Inclusion criteria

  • With signs of upper motor neuron lesion,
  • Suprasacral spinal cord injury,
  • Normal urinary ultrasound findings
  • Planned urodynamics

Exclusion criteria

  • Neurological disease other than spinal cord injury
  • Urinary tract infection
  • Urinary obstruction
  • History of urinary tract Stones
  • Diabetes, hypertension
  • History of urinary surgery,
  • Sacral injury
  • Second motor neuron lesions (such as cauda equina, or cauda conus)

The control group

Inclusion criteria

  • Normal urinary ultrasonography

Exclusion criteria

  • Neurological disease
  • Urinary tract infection
  • Urinary obstruction
  • History of urinary tract Stones
  • Diabetes, hypertension

Treatment and study plan

Doppler ultrasound, Urodynamic assessment.

Diagnostic Test

The patients included in the study group were given 600 cc of water in the morning and the Doppler ultrasound was performed 30 minutes later

Urodynamic assessment.

Diagnostic Test

A transurethral double lumen catheter was used to measure intravesical pressure in the urodynamic unit for the patients in the study group immediately after the use of the Doppler USG

Primary outcomes

  1. doppler USG

    Time frame: 15-30 minute

    The patients included in the study group were given 600 cc of water in the morning and the Doppler USG was performed 30 minutes later

  2. Urodynamic assessment.

    Time frame: 30 minute

    A transurethral double lumen catheter was used to measure intravesical pressure in the urodynamic unit

Sponsors and collaborators

Lead sponsor

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Other

Registry information

Official study title

The Characteristics of Ureteric Jet Doppler Waveforms and Factors Affecting Them in Patients With Spinal Cord Injury

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Oct 6, 2022
Registry last updated
Oct 7, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.