Uninvasive Cardiac Output Monitoring (USCOM) in Critically Ill Children: Validation and Prediction of Hemodynamic Instability

Hemodynamically unstable ventilated PICU & PCICU patients, which a decision for commencement in inotropic therapy or fluid bolus has been made, will be recruited. Hemodynamic measurements will be carried out before and after therapy have been made, including customary hemodynamic parameters, echocardiography and USCOM studies.

All parameters will be analyzed for fluid responsiveness or inotropic therapy prediction. Trend in USCOM parameters will be compared to echocardiography CO parameters.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hemodynamic Instability Critical Illness Disease Attributes Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

2 day–18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Schneider's children medical center

Petah Tikva, Israel

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Pediatric critically ill ventilated patients admitted to PICU & PCICU
Hemodynamically unstable which a decision for commencement in inotropic therapy or fluid bolus has been made
parental concent

Exclusion criteria

Cardiac shunt
Aortal anomaly \\ Repair
Tracheostomy
Parental refusal to participate

Treatment and study plan

Primary outcomes

Raise>10% in cardiac index following therapy

Time frame: 20 minutes

Sponsors and collaborators

Lead sponsor

Rabin Medical Center

Other

Registry information

Important dates

Study start: 2016
Primary completion: 2020
Study completion: 2020
First posted: Oct 26, 2016
Registry last updated: Mar 16, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed