Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07182760

Ultrasound to Detect Splenomegally in Patients With Isolated Thrombocytopenia

Investigate prevalence of splenomegally in patients with isolated thrombocytopenia.

Asess effect of splenomegally in clinical picture ,Complication, treatment response and disease outcome To explain possible causes of splenomegally in patients with isolated thrombocytopenia

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Primary Immune Thrombocytopenic Purpura Amegakaryocytic Aplasia Autoimmune Diseases With Secondary ITP Lymphoproliferative Disorder With Secondary ITP Unilineage Myelodysplastic Syndrome ( Megakaryocyte Dysplasia)

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients more than 18 years admitted with isolated thrombocytopenia due to primary Immune thrombocytopenic purpura amegakaryocytic aplasia Unilineage myelodysplastic syndrome ( megakaryocyte dysplasia) lymphoproliferative disorder with secondary ITP autoimmune diseases with secondary ITP Willingness to participate in the study Admitted patients or those who follow at hematology outpatients clinic

Exclusion criteria

EDTA induced pseudothrombocytopenia Platelet satellitism Drug induced thrombocytopenia Heparin induced thrombocytopenia / thrombosis syndrome post transfusion purpura Disseminated intravascular coagulopathy patients less than 18 years old patients with bicytopenia or pancytopenia Pregnancy

-

Treatment and study plan

Primary outcomes

  1. Investigate prevalence of splenomegally in patients with isolated thrombocytopenia. Asess effect of splenomegally in clinical picture ,Complication, treatment response and disease outcome

    Time frame: Baseline

    • How many patients with isolated thrombocytopenia present with splenomegaly
    • Do patients with splenomegaly experience different complications compared to those without splenic enlargement
    • Is there a difference in treatment response between patients presenting with splenomegaly and those without splenic involvement

Study contacts

Contact information is provided by the study sponsor or research team.

Karim Ashraf, Resident

CONTACT

[email protected]

+20 ext. 01019954118

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Clinicopathologic Significance of Splenomegally in Adult Patients With Isolated Thrombocytopenia

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Sep 19, 2025
Registry last updated
Sep 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.