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OpenTrials
Completed

NCT Number: NCT02024724

Ultrasound Guided Trigeminal Nerve Block for Typical or Atypical Facial Pain

Trigeminal neuralgia is a craniofacial pain syndrome that is typically characterized by unilateral severe, recurrent, electrical pain in one or more distributions of the trigeminal nerve. Current treatment strategies include oral medications as first line therapy with surgical interventions reserved for those patients who are refractory to medications or unable to tolerate medication side effects. Despite these current treatment options, many patients continue to have symptoms. Ultrasound-guided trigeminal nerve block allows for fine adjustment of the needle tip and direct observation of the medicine.

Local anesthetic and steroids have been successfully used for diagnostic and or therapeutic nerve pain with great success. Steroids can be short or long acting in duration with varying side effects. If there exists a difference in duration of action, using the longer acting drug will provide a greater period of symptom relief for the patient and may allow the patient to undergo fewer interventional procedures.

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Anesthesiology Pain Medcine Center

Chicago, Illinois, 60611, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients presenting to the Northwestern Pain Center who are eligible and scheduled to receive a ultrasound-guided trigeminal nerve block.

Exclusion criteria

  • Exclusion is the same for patients who are not eligible for ultrasound guided nerve blocks.

Treatment and study plan

Bupivacaine

Drug

4 mL of 0.25% bupivacaine

Triamcinolone

Drug

40 mg of Triamcinolone

Dexamethasone

Drug

4 mg of Dexamethasone

Primary outcomes

  1. The Proportion of Subjects Reporting at Least 50% Overall Pain Relief

    Time frame: 2 weeks

    The number of subjects reporting a minimum of 50% pain relief after receiving the injection.

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Registry information

Official study title

Phase 4 Study Comparing of Dexamethasone to Triamcinolone for Ultrasound-guided Trigeminal Nerve Block: A Randomized Controlled Trial.

Important dates

Study start
2013
Primary completion
2016
Study completion
2017
First posted
Dec 31, 2013
Registry last updated
Jul 11, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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