Hala Saad Abdel-Ghaffar
Asyut, Assiut Governorate, 715715, Egypt
NCT Number: NCT02976597
Transversus abdominis plane (TAP) block is a novel type of peripheral nerve block that involves innervations of the anterolateral abdominal wall derived from T6-L1.It provides adequate post-operative pain relieve following the various abdominal surgeries. Theoretically, TAP block may replace the need for epidural analgesia after abdominal operations. The oblique subcostal approach of the TAP (OSTAP) block, which was de¬scribed by (Hebbard et al, 2010) , has been reported to provide analgesia to the entire anterior abdomen.
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Notify Me18 year–60 year
All sexes
Interventional
Phase 2 / Phase 3
Asyut, Assiut Governorate, 715715, Egypt
The transversus abdominis plane (TAP) technique, originally described by involves injection of local anaesthetic in the plane between the internal oblique and transversus abdominis muscle layers, with the aim of anaesthetising the intercostal nerves supplying the abdominal wall. Initially, the block used surface landmarks of the triangle of Petit (latissimus dorsi posteriorly, external oblique superiorly, iliac crest inferiorly) and a double fascial 'pop' (loss of resistance) to guide placement of the local anaesthetic. More recently, ultrasonography has been used to guide the delivery of the injectate into the appropriate plane, thereby increasing the accuracy of the Technique.
The duration of the TAB is limited to effect of administered local anesthetics. To prolong the block's duration, adjuvant medications were added to LA to magnify the effect of TAP block . Opiates such as morphine and tramadol have peripheral and central analgesic effects. Opiate receptors are present at the terminals of afferent peripheral nerves; therefore, administration of opiates peripherally might provide a significant analgesic effect.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
BMI< 30kg/m2.
Exclusion criteria
Bupivacaine 0.25% 20ml on each side Sonar guided TAP block. After careful aspiration injection of 20ml of 0.25% bupivacaine will be performed and hypoechoic layer will be detected on ultrasound then the maneuver will be repeated on the other side
Other names: BUCAIN Sonar guided
Morphine 10mg will be added to bupivacaine in sonar guided- TAP block divided into 5mg on each side.
Other names: Morphine injection
Morphine 15mg will be added to bupivacaine in sonar guided- TAP block divided into 7.5mg on each side.
Other names: Morphine injection
Time frame: 24 hours
The 24 hours postoperative verbal rating scale score on cough
Time frame: 24 hours
The total 24 hours consumption of analgesic drugs taken.
Time frame: 24 hours
The time from end of the operation, PACU admission and the request for analgesic drugs.
Time frame: 24 hours
Measurment of lung function by spirometry.
Time frame: 24 hours
Recording and treatment of adverse effects.
Assiut University
Other
Morphine as an Adjunct in Sonar Guided Transversus Abdominis Plane Block for Postoperative Analgesia in Patients Undergoing Abdominal Surgery.
Acronym: TAB
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