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NCT Number: NCT07745972

Ultrasound-Guided Recto-Intercostal Fascial Plane Block in Laparoscopic Cholecystectomy

The aim of the study is to reduce postoperative pain by performing rectointercostal block in L/S cholecystectomy surgeries. Main goal is to provide well managed post-operative analgesia.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Istinye University Liv Topkapı Hospital

Istanbul, 34050, Turkey (Türkiye)

About this study

The patients will be divided into two groups and general anesthesia will be applied to all of them. There will be no regional anesthetic technique to be performed, on the other hand, rectointercostal nerve block will be applied to patients in the other group before the patients are extubated. Study randomization is done with computer-generated randomization codes (computer-generated) by a physician who will not participate in patient follow-up. Interfascial plane block (rectointercostal block) will be given to the anesthesiologist in a sealed envelope by an independent assistant staff outside the study, the patient will not know which block is applied. The anesthetist who made the block will not participate in the pain follow-up of the patients. Postoperative pain assessment and data collection will be performed by another anesthetist blinded to the study.

For the standardization, the block procedure will be performed by an experienced anesthesiologist who has performed at least 20 previous successful and uncomplicated procedures.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI < 35 kg/m²
  • Patients with ASA scores I and II

Exclusion criteria

  • Patients who do not want to be included in the study
  • Psychiatric and neurological disease with blurred consciousness
  • Patients with ASA > 3
  • BMI > 35 kg/m²
  • Abnormality in coagulation parameters
  • History of allergy to local anesthetic drugs
  • Infection at the injection site

Treatment and study plan

Rectointercostal facial plane block using bupivacaine 0.25%

Procedure

Under ultrasound guidance, a total of 30 mL of solution will be administered bilaterally between the rectus abdominis muscle and the intercostal muscles, at the level of the 6th and 7th costal cartilages bilaterally.

Primary outcomes

  1. Postoperative opioid consumption

    Time frame: 24 hours

    Contramal consumption in the first 24 hours after surgery

Secondary outcomes

  1. NRS Scores

    Time frame: At 1,3, 6, 12, 18, 24 hours

    NRS scores in the first 24 hours after surgery

  2. Quality of recovery

    Time frame: 24 hours

    QR15 scores

  3. Nausea and vomiting

    Time frame: At 1,3, 6, 12, 18, 24 hours

    Nausea and vomiting scores in the first 24 hours

Study contacts

Contact information is provided by the study sponsor or research team.

Bora Bilal, Proffesor

CONTACT

[email protected]

+902124446623

Sponsors and collaborators

Lead sponsor

Istinye University

Other

Registry information

Official study title

Evaluation of the Effect of Ultrasound-Guided Bilateral Recto-Intercostal Fascial Plane Block on Postoperative Pain, Opioid Consumption, and Quality of Recovery in Laparoscopic Cholecystectomy Surgery: A Prospective, Randomized, Double-Blind Controlled Clinical Study

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 4, 2026
Registry last updated
Aug 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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