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OpenTrials
Completed

NCT Number: NCT06048744

Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Nephrectomy

The patients will be randomly allocated into two equal groups using a computer program.

Group A: will receive U S guided external oblique intercostal block after induction.

Group B:

Patients will receive US guided erector spine block after induction.

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Key information

Conditions

Post Operative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Menoufia university

Cairo, Shibin Elkom, Egypt

About this study

Patients will be premedicated with IV midazolam (0.05 mg/kg). Under standard monitoring including Electrocardiography, Non-Invasive Blood Pressure, and Pulse Oximetry. General Anesthesia will be induced with Fentanyl (1-2 μg/kg), Propofol (2-3 mg/kg), and Atracurium (0.5-0.8 mg/kg). Pressure controlled Volume guarantee Ventilation mode will be used to maintain O2 Saturation Above 98%. Anesthesia will be maintained with Isoflurane 1.2 Minimum Alveolar Concentration inhalation

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Eligible patients will be older than 21 years old with American society of anesthesiology ASA physical status I& II&III scheduled for elective (Subcostal) Nephrectomy

Exclusion criteria

  • Patients who are:
  • Uncooperative.
  • Having allergy to any of the study drugs.
  • Known abuse of alcohol or medication.
  • Having Local infection at the site of injection or systemic infection.
  • Pregnancy.
  • With coagulation disorders or on anticoagulation therapy.

Treatment and study plan

external oblique intercostal block

Procedure

U S guided external oblique intercostal block after induction.

Erector Spine block

Procedure

US guided erector spine block after induction

Primary outcomes

  1. time for first rescue analgesia

    Time frame: day 0

    hours

Secondary outcomes

  1. visual analogue score VAS score

    Time frame: 24 hours

    (a scale from 0 to 10 where 0 is interpreted as no pain, 1-4 mild pain, 5-6 moderate pain, 7-10 severe pain) will be recorded 15 min after extubation (as soon as the patient will be alert enough to report pain)

  2. the number of rescue analgesics

    Time frame: 24hours

    numbers'

Sponsors and collaborators

Lead sponsor

Menoufia University

Other

Registry information

Official study title

Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Postoperative Analgesia in Patients Undergoing Subcoastal Nephrectomy: A Randomised Trial

Acronym: EOINBvsESB

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
Sep 21, 2023
Registry last updated
Jan 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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