Ultrasound-guided Blood Sampling Drawing for Microbiological Analysis in the Critically Ill

This study will test the feasibility of ultrasound-guided sterile blood sampling for critically ill patients with suspected sepsis requiring blood culture. The aim of the study is to evaluate the feasibility and safety of the use of ultrasound for blood cultures in a population of patients which can present difficult venous access and requiring more than one venipuncture attempt in general clinical practice

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Key information

Conditions

Sepsis Diagnosis Disease Infections Inflammation Pathologic Processes Pathological Conditions, Signs and Symptoms Septic Shock Shock Shock, Septic Systemic Inflammatory Response Syndrome

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patients (18 year-old)
admitted to intensive care unit
suspected sepsis requiring blood cultrure

Exclusion criteria

pregnancy
infections requiring respiratory isolation
burns or skin disease involving arms and/or more than 60% of body surface

Treatment and study plan

Ultrasound-guided venipuncture

Diagnostic Test

Venipuncture will be performed using ultrasound to identify the most appropriate vessel and guide the puncture

Primary outcomes

Number of attempted venipunctures

Time frame: One hour after clinical decision of blood culture execution

Evaluation of the feasibility of ultrasound-guided venipuncture for blood samples in patients requiring ,microbiological analysis. Feasibility will be evaluated in terms of number of needed attempts of venipuncture

Secondary outcomes

Incidence of possible complications (accidental arterial puncture, visible ematoma)

Time frame: One hour after clinical decision of blood culture execution

Evaluation of safety of venipuncture in terms of possible complications (accidental arterial puncture, ematoma)
Incidence of contamination of ultrasound-guided venipuncture

Time frame: One hour after clinical decision of blood culture execution

Evaluation of blood sample bacterial contamination compared to blind puncture

Study contacts

Contact information is provided by the study sponsor or research team.

Antonio M Dell'Anna, M.D.

CONTACT

[email protected]

3803679256

Sponsors and collaborators

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Other

Registry information

Official study title

Use of Ultrasound for Blood Sample Drawing for Microbiological Analysis in Critically Ill Patients:he ECOVEN Feasibility Study

Acronym: ECOVEN

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Dec 5, 2023
Registry last updated: Mar 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed