Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric Population
NCT06559137
Agnosia, Analgesia
Frisco, Texas, United States
View Trial DetailsNCT Number: NCT07736989
Cesarean delivery is one of the most frequently performed surgical procedures worldwide, and effective postoperative pain management is essential to facilitate early mobilization, maternal-infant bonding, breastfeeding, and overall recovery. Ultrasound-guided transversalis fascia plane block (TFPB) has become an increasingly utilized component of multimodal analgesia following cesarean delivery because it provides effective somatic analgesia of the lower anterior abdominal wall. Adjuvants such as dexamethasone are frequently added to local anesthetics with the aim of prolonging block duration and improving postoperative analgesia; however, evidence regarding the clinical benefits of dexamethasone as an adjunct in TFPB remains limited.
At our institution, bilateral ultrasound-guided TFPB is routinely performed for postoperative analgesia in patients undergoing cesarean delivery under spinal anesthesia, provided there is no contraindication and informed consent has been obtained. According to the treating anesthesiologist's routine clinical preference, dexamethasone may be added to the local anesthetic solution in some patients, whereas others receive local anesthetic alone. This retrospective cohort study will review the medical records and postoperative follow-up forms of patients who underwent cesarean delivery between November 1, 2025, and June 30, 2026. Postoperative analgesic outcomes, including opioid consumption, pain scores, time to first analgesic request, postoperative nausea and vomiting, recovery quality, and block-related adverse events, will be compared between patients receiving bilateral TFPB with dexamethasone and those receiving bilateral TFPB without dexamethasone. The findings are expected to provide real-world evidence regarding the potential contribution of dexamethasone to the analgesic efficacy of bilateral TFPB following cesarean delivery.
Trial opening soon.
Get Notified18 year–50 year
Female
Observational
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: First 24 hours after surgery
Total opioid consumption delivered through the patient-controlled analgesia device during the first 24 hours after surgery, expressed in mg. Patients were instructed to use the PCA device when the Numeric Rating Scale pain score was 4 or higher.
Time frame: 1, 3, 6, 9, 12, 18, and 24 hours after surgery
Pain intensity assessed using the Numeric Rating Scale (NRS, 0-10).
Time frame: Within the first 24 postoperative hours
Time from completion of surgery to the first patient-controlled analgesia (PCA) demand for postoperative analgesia.
Time frame: 24 hours after surgery
Quality of recovery assessed using the ObsQoR-10 questionnaire.
Contact information is provided by the study sponsor or research team.
Selma Kahyaoglu
CONTACT
selma basyigit
CONTACT
Bahçeşehir University
Other
Postoperative Analgesic Outcomes After Bilateral Ultrasound-Guided Transversalis Fascia Plane Block With or Without Dexamethasone in Cesarean Delivery: A Retrospective Cohort Study
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