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NCT Number: NCT07062068

Ultrasound-Guided BCV and IJV in ICU Patients

This is a prospective randomized clinical trial aiming to compare the success rate, complications, and insertion time between ultrasound-guided brachiocephalic vein (BCV) and internal jugular vein (IJV) cannulation in mechanically ventilated patients in the intensive care unit (ICU). The goal is to determine whether BCV access offers a safer or more effective alternative in critically ill patients requiring central venous catheter placement.

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Key information

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Central venous cannulation is a common and essential procedure in the management of critically ill patients, especially those requiring mechanical ventilation. Traditionally, the internal jugular vein (IJV) has been the preferred site. However, the brachiocephalic vein (BCV) has recently gained attention due to its potentially favorable anatomical location and reduced complication rates.

This study is designed to compare the outcomes of ultrasound-guided cannulation of the BCV versus the IJV, focusing on parameters such as success rate of insertion on first attempt, total cannulation time, and incidence of complications such as arterial puncture, pneumothorax, or hematoma formation. The study will be conducted on adult patients admitted to the ICU and undergoing mechanical ventilation

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

100 patients with age between ( 18 - 50 years old ) ventilated in ICU with need central venous access , with physical status II or III according to ASA classification .

Exclusion criteria

  • refusal of relatives of patients
  • Any contraindication of Central venous line insertion as thrombocytopenia , coagulopathy …. Etc
  • any suspected or documented thrombus inside vein
  • any congenital or acquired musculo-skeletal deformities of neck or clavicle
  • any active infections or signs of inflammation over insertion site
  • any previous procedures performed at the cannulation site

Treatment and study plan

ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients

Procedure

For Arm ( candidates for BCV cannulation ) :

by ultrasound guided we insert Central venous catheter in BCV under complete aseptic condition For Arm ( candidates for IJV cannulation ) by ultrasound guided we insert central venous catheter in IJV under complete aseptic conidtion we do comparison between the 2 arms as regard : 1st pass success rate , complications and failure rate in ventilated patient in ICU .

Primary outcomes

  1. cannulation failure rate

    Time frame: Baseline

    Failure to cannulate selected vein at 1st attempt

Study contacts

Contact information is provided by the study sponsor or research team.

Hasnaa mohey ibrahim, resident doctor

CONTACT

[email protected]

0201156950052

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Comparative Study Between Ultrasound-Guided Brachiocephalic Vein and Internal Jugular Vein Cannulation in Mechanically Ventilated ICU Patients

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 14, 2025
Registry last updated
Jul 14, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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