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Completed

NCT Number: NCT02100579

Ultrasound-guided Adductor Canal Block for Total Knee Replacement

Total knee arthroplasty is associated with intense early postoperative pain. Fast track recovery programs including early therapy protocols and early hospital discharge are being implemented at various hospitals. The postoperative analgesic pain regimen should enhance functional recovery in addition to providing efficient analgesia with minimal side effects. Adductor canal blockade is commonly used to provide postoperative analgesia for total knee arthroplasty (TKA) surgery. The investigators hypothesize that an ultrasound guided adductor canal block will lower narcotic consumption and improved overall satisfaction compared to ultrasound guided sham block with normal saline (placebo) for patients undergoing minimally invasive TKA surgery.

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Key information

Conditions

Complications; Arthroplasty Knee Injuries Leg Injuries Wounds and Injuries

Age range

40 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Northwestern University Feinberg School of Medicine

Chicago, Illinois, 60611, United States

About this study

The investigators hypothesize that an ultrasound guided adductor canal block will lower narcotic consumption and improved overall satisfaction compared to ultrasound guided sham block with normal saline (placebo) for patients undergoing minimally invasive TKA surgery.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants 40 to 75 years old who are presenting for minimally invasive total knee arthroplasty under spinal anesthesia

Exclusion criteria

  • Patient refusal
  • American Society of Anesthesiologists physical status classification of 4 or higher
  • Pre-existing neuropathy in the femoral or sciatic distribution
  • Coagulopathy
  • Infection at the site
  • Chronic opioid use (greater than 3 months)
  • Pregnancy
  • Medical conditions limiting physical therapy participation
  • Any other contra-indication to regional anesthesia

Treatment and study plan

Bupivacaine

Drug

10 ml of 0.25% bupivacaine

Other names: Sensorcaine

Preservative free normal saline

Drug

10 ml of preservative free normal saline

Other names: 0.9% sodium chloride

Primary outcomes

  1. Opioid Consumption (mg morEq)

    Time frame: 36 hours

    Opioid consumption (morphine equivalents)

Secondary outcomes

  1. Visual Analog Scale Pain Score

    Time frame: Pain burden at 36hr

    Visual Analog Scale pain score; 0 = no pain, 10 = excruciating pain) in the knee recorded every 6 hours up to 36hrs following surgery.

  2. Length of Hospitalization

    Time frame: 0 to 192 hours

    The average time to discharge in hours. Participants were discharged home went physical therapy criteria were met.

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Registry information

Official study title

Ultrasound-guided Adductor Canal Block for Total Knee Replacement: a Randomized, Double-blind Placebo Controlled Trial.

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Apr 1, 2014
Registry last updated
Jul 11, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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