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NCT Number: NCT06824506

Ultrasound for Postop Lung Issues in Low-Flow Anesthesia

Detecting possible atelectasis and other respiratory problems that may develop immediately after extubation via lung ultrasonography can reduce pulmonary complications by performing necessary interventions such as oxygen support, respiratory exercises, mobilization, and non-invasive mechanical ventilation applications at an early stage. In addition, although low-flow anesthesia is frequently used in daily anesthesia practice, publications showing the effects of its use in laparoscopic cholecystectomy operations on pulmonary complications are limited. On this occasion, this study can be presented as a contribution to the literature.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara Ataturk Sanatorium Research and Training Hospital

Ankara, Turkey (Türkiye)

Location status: Recruiting

Location contact

Mustafa Ozgur CIRIK, Assoc. Prof.

CONTACT

[email protected]

90 312 567 70 00 ext. 2031

About this study

Postoperative atelectasis is a common complication that can develop in all patients receiving general anesthesia. The frequency of atelectasis increases due to increased intraabdominal pressure, especially in laparoscopic surgeries performed with pneumoperitoneum. For this reason, in order to prevent postoperative complications related to the lungs, it is extremely important to recognize atelectasis at an early stage, as well as to recognize the mechanisms that will cause atelectasis and avoid them.

Lung ultrasonography (Lung USG) draws attention for the rapid, cheap, safe and reliable detection of postoperative atelectasis. The fact that it can be applied at the bedside and can be easily repeated makes this method valuable. In the literature and in daily practice, it is seen that anesthesiologists commonly apply inhalation anesthesia with different fresh gas flow (FGF) rates during general anesthesia.

As defined by Baker and Simionescu, in low-flow anesthesia, FGF varies between 0.5 and 1 liter per minute. It has been shown that all types of flow are safe with modern anesthesia machines.

This study aims to demonstrate the effect of low-flow anesthesia (LFA) on pulmonary complications and, in particular, atelectasis that may develop after laparoscopic cholecystectomy operations, using a non-invasive, rapidly applicable, and proven method such as Lung USG.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with informed consent
  • Patients scheduled for laparoscopic cholecystectomy
  • Patients with a Body Mass Index between 18-35 kg/m²
  • Patients in the American Society of Anesthesiologist (ASA) 1-2-3 category

Exclusion criteria

  • Patients with emergency surgery planned
  • Patients with ASA 4 and above
  • Patients with lung disease
  • Patients who have undergone thoracic surgery
  • Pregnancy
  • Patients with a preoperative Lung Ultrasound Score of 2 or 3 in any lung region

Treatment and study plan

No-intervention

Other

No interventions will be performed by the research team.

Primary outcomes

  1. incidence of postoperative atelectasis

    Time frame: 1 hour peroperatively

    Incidence of postoperative atelectasis determined by lung ultrasonography in patients undergoing laparoscopic cholecystectomy with low-flow anesthesia

Secondary outcomes

  1. incidence of other postoperative pulmonary complications

    Time frame: 1 hour peroperatively

    Other postoperative pulmonary complications that may develop and be detected by ultrasonography such as pneumothorax, pleural effusion, pulmonary edema

Study contacts

Contact information is provided by the study sponsor or research team.

Hilal SAZAK, MD

CONTACT

[email protected]

+90 312 356 90 00

Necla DERELI, MD

CONTACT

Sponsors and collaborators

Lead sponsor

Ankara Ataturk Sanatorium Training and Research Hospital

Other Gov

Registry information

Official study title

Evaluation of Early Postoperative Pulmonary Complications That Can be Detected by Ultrasonography in Patients Undergoing Laparoscopic Cholecystectomy With Low-flow Anesthesia

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Feb 13, 2025
Registry last updated
Jun 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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