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NCT Number: NCT06654778

Ultrasound Evaluation of Preventive Measures for Postoperative Lung Atelectasis After Surgery

the aim of this prospective randomized blinded clinical study will be to assess the ultrasound evaluation of different preventive measures of post operative lung atelectasis in abdominal surgeries; these measures include ventilation and fluid measures

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Key information

Conditions

Pulmonary Atelectasis, Postoperative Lung Diseases Pulmonary Atelectasis Respiratory Tract Diseases

Age range

30 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Al-Azhar university

Asyut, Egypt

About this study

ultrasound evaluation for application of different preventive measures of post operative lung atelectasis, including positive end-expiratory pressure, lung recruitment maneuvers, and restrictive fluid management.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA physical status I or II, of either gender.
  • BMI < 40
  • Age 30-60 years
  • scheduled for elective abdominal surgeries

Exclusion criteria

  • Patient refusal
  • American Society of Anesthesiologists (ASA) physical status classification system more than II
  • BMI > 40 .
  • Psychiatric disorders
  • History of chest disorders such as asthma and obstructive pulmonary disease (COPD).
  • History of Previous Thoracic Procedures.
  • Pregnancy

Treatment and study plan

PEEP

Other

Patients will be ventilated with PEEP of 8 cm H2O and fluid management: 500 ml of Ringer's lactate in the recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery.

PEEP/RM

Other

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and fluid management: 500 ml of Ringer's lactate in recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery

PEEP/RM/RF

Other

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and restrictive fluid management (RF). Ringer's lactate at a rate of 3 mL/kg/hour from the beginning to the end of the surgery

Primary outcomes

  1. Lung ultrasound assessment of postoperative pulmonary atelectasis at the end of surgery

    Time frame: at the end of surgery before emergence from GA.

    Lung ultrasound assessment of postoperative pulmonary atelectasis at the end of surgery.

    The Lung Ultrasound Score (LUS): the key points based on ultrasound findings:

    I. 0 points: (N) Normal aeration (presence of lung sliding with A-lines or <2 separate B-lines).

    II. 1 point: (B1) Moderate loss of lung aeration (≥3 well-defined B lines). III. 2 points: (B2) Severe loss of lung aeration (coalescing B-lines). IV. 3 points: (C) Complete loss of lung aeration (pulmonary consolidations). Total Score: points will be distributed according to the worst ultrasound pattern observed: N = 0, B1 lines = 1, B2 lines = 2, C = 3. The LUS score ranging between 0 and 36 was calculated as the sum of points.

Secondary outcomes

  1. Lung ultrasound assessment

    Time frame: before induction of general anesthesia

    Lung ultrasound assessment of atelectasis

  2. Lung ultrasound assessment

    Time frame: 5 minutes post induction of general anesthesia

    Lung ultrasound assessment of atelectasis

  3. Lung ultrasound assessment

    Time frame: 15 minutes after patients arrive to PACU

    Lung ultrasound assessment of atelectasis

  4. Lung ultrasound assessment

    Time frame: 60 minutes after patients arrive to PACU

    Lung ultrasound assessment of atelectasis

  5. arterial blood gases

    Time frame: 5 minutes post induction of general anesthesia

    Pao2, spo2, paco2, pao2/fio2

  6. arterial blood gases

    Time frame: before emergence from general anesthesia

    Pao2, spo2, paco2, pao2/fio2

  7. arterial blood gases

    Time frame: 15 minutes after patients arrive to PACU

    Pao2, spo2, paco2, pao2/fio2

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

Ultrasound Evaluation of Different Preventive Measures of Post Operative Lung Atelectasis After Upper Abdominal Surgeries: Ventilation and Fluid Measures

Acronym: LUS/PEEP/RM

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Oct 23, 2024
Registry last updated
Dec 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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