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Completed

NCT Number: NCT06575504

Ultrasonographical of Suprarenal Gland in High Risk Neonates

Observation study The aim is to study the suprarenal blood flow among high-risk neonates and its relation to the risk factors

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Key information

Age range

1 day–10 day

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of medicine for girls

Cairo, Pediatrics/neonatology, 11351, Egypt

About this study

Ultrasonographical study of the suprarenal gland in high risk newborn infants Al-Zhrraa University hospital Sample size 105 Inclusion criteria: 1- High-risk newborn 2- Need NICU admission Exclusion criteria: Cases with Major congenital anomalies and NEC Primary outcome: Abnormal suprarenal blood flow Informed consent will be obtained from all parents and mothers of the newborns enrolled in the study.

All cases will be subjected to - Full history taking: (prenatal -natal - postnatal). According to the routine admission sheet of NICU of Alzahraa University Hospital, Faculty of Medicine for girls, AL-Azhar University, Cairo, Egypt.

Through clinical examination (APGAR score -estimation of gestational age using modified Ballard score "Ballard, 1991" - body weight - severity of respiratory illness using Downs score and Silverman's score).

Laboratory investigations:

  • Blood gases.
  • Serum electrolytes and blood glucose.
  • CBC. CRP.
  • Liver and kidney functions. Radiological evaluation: in the form of Abdominal and chest x-ray. Ultrasonographical studies were done for suprarenal gland blood flow. - Statistical Analysis, Data were collected, revised, coded, and entered into the statistical package for social science (SPSS)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • High risk neonates

Exclusion criteria

  • congenital anomalies

Treatment and study plan

Ultrasonographical examination

Diagnostic Test

Study size and Doppler / blood flow / of the suprarenal gland

Primary outcomes

  1. Adrenocortical insufficiency

    Time frame: 12 months

    Blood flow velocity RI ED TMAX

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

Ultrasonographical Study of Suprarenal Gland in High Risk Neonates

Acronym: USSGneonates

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Aug 28, 2024
Registry last updated
Aug 28, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.