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OpenTrials
Completed

NCT Number: NCT07370376

Ultrasonographic of Diaphragmatic Function in Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) is associated with altered respiratory mechanics, including diaphragmatic function. Ultrasonography provides a non-invasive tool to assess diaphragmatic structure and performance, which may correlate with OSA severity.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Mohamed AbdElmoniem

Al Mansurah, 35516, Egypt

About this study

Obstructive sleep apnea (OSA) is associated with altered respiratory mechanics, including diaphragmatic function. Ultrasonography provides a non-invasive tool to assess diaphragmatic structure and performance, which may correlate with OSA severity. The aim of the study is to evaluate diaphragmatic function in OSA patients using ultrasonography and to investigate its relationship with OSA severity and sleep-related parameters.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients visiting the Sleep Disordered Breathing (SDB) Unit at the Chest Medicine Department and diagnosed with obstructive sleep apnea (OSA) were included if they met the following criteria:
  • Age 18-65 years.
  • Willingness to participate in the study.

Exclusion criteria

  • Patients were excluded if they had any of the following conditions:
  • Refusal to participate in the study
  • Age <18 or >65 years
  • Systemic organ failure, including heart failure, stroke, renal failure, or liver failure; Uncontrolled diabetes mellitus
  • Diagnosed obesity hypoventilation syndrome (OHS) or other sleep disorders apart from OSA
  • Chronic respiratory diseases such as COPD, bronchial asthma, or restrictive lung disease
  • OSA patients already receiving therapy (CPAP, oral appliances, or upper airway surgery)
  • Neuromuscular disorders or other conditions affecting diaphragmatic function (malnutrition, chest trauma, or immobility)
  • Use of steroids or uncontrolled autoimmune diseases.

Treatment and study plan

Primary outcomes

  1. Ultrasonographic Assessment of Diaphragmatic Function in Obstructive Sleep Apnea Patients

    Time frame: 6 months

    All participants underwent diaphragm thickening fraction (DTF) as a percentage (%)

Sponsors and collaborators

Lead sponsor

Mansoura University

Other

Registry information

Official study title

Ultrasonographic Assessment of Diaphragmatic Function in Obstructive Sleep Apnea Patients

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
Jan 27, 2026
Registry last updated
Jan 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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