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NCT Number: NCT07314840

Ultrasonographic Examination of Other Enthesitis Sites in Patients With Lateral Epicondylitis

Lateral epicondylitis (LE) is the tendinopathy of the common extensor tendon. Although exact etiology remains unclear, it is believed to be caused by overuse.

Even though, genetics factor related to tendinopathies were defined accompanying tendinopathies in patients with LE is yet to be studied.

Madrid sonographic enthesitis index (MASEI) is an ultrasound based scoring system, developed for the evaluation of the enthesitis. Initially developed for ankylosing spondylitis, its usage has also become widespread in other musculoskeletal diseases.

The aim of this study is to calculate the MASEI score in patients diagnosed with LE, and compare it to healthy volunteers.

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Key information

Conditions

Lateral Epicondylitis Arm Injuries Elbow Injuries Elbow Tendinopathy Lateral Elbow Tendinopathy (Tennis Elbow) Muscular Diseases Musculoskeletal Diseases Tendinopathy Tendon Injuries Tennis Elbow Wounds and Injuries

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Marmara University

Istanbul, Maltepe, 34844, Turkey (Türkiye)

Location status: Recruiting

Location contact

Arda Can Kasap, MD

CONTACT

[email protected]

905384590119

Arda Can Kasap, MD

SUB_INVESTIGATOR

Naime Evrim Karadağ Saygı, Prof. M.D.

SUB_INVESTIGATOR

İlker Yağcı, Prof. M.D.

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Tenderness with palpation at the lateral epicondyle
Pain aggravated with resisted wrist extension

Exclusion criteria

History of rheumatologic diseases
History of elbow, knee or ankle surgery
History of corticosteroid injections on elbow, knee or ankle
History of peripheral neuropathy
Acute trauma

Treatment and study plan

Madrid Sonographic Enthesitis Index

Diagnostic Test

Patients will be evaluated with ultrasound at 6 different locations on each side, for total of 12 locations. These will be insertion points of triceps brachii tendon, quadriceps tendon, proximal and distal patellar tendons, achilles tendon and the plantar fascia. Evaluation parameters are the structure and thickness of the tendon, the presence of calcifications or enthesophytes, erosions in the bone, regional bursitis, and the presence of power-Doppler signal in the entheses.

Other names: MASEI

Primary outcomes

Madrid Sonographic Enthesitis Index

Time frame: At enrollment

Patients will be evaluated with ultrasound at 6 different locations on each side, for total of 12 locations. At each location; structure and thickness of the tendon, the presence of calcifications or enthesophytes, erosions in the bone, regional bursitis, and the presence of power-Doppler signal will be noted. Each parameter has a point of its own. Points obtained from each parameter will be added and total MASEI score (0-136) will be calculated. Higher scores indicate the presence of enthesitis.

Study contacts

Contact information is provided by the study sponsor or research team.

Arda Can Kasap, MD

CONTACT

[email protected]

905384590119

Sponsors and collaborators

Lead sponsor

Marmara University

Other

Registry information

Official study title

Ultrasonographic Examination of Other Enthesitis Sites in Patients With Lateral Epicondylitis: A Cross-Sectional Study

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Jan 2, 2026
Registry last updated: Jan 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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