Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07044986

Ultrasonographic Evaluation of the Ulnar Nerve in Individuals With and Without Generalized Joint Hypermobility

This study will include 30 individuals diagnosed with Generalized Joint Hypermobility (GJH) based on the Beighton score and 30 healthy controls without GJH. Participants will undergo Tinel's test and the flexion-compression test. The presence of ulnar nerve-related symptoms such as pain and numbness will be recorded. Ultrasonographic evaluation of the ulnar nerve will be performed at the level of the medial epicondyle, as well as 2 cm proximal and distal to it. Cross-sectional area and diameter of the ulnar nerve will be measured at each site, repeated three times, and the average will be used. Additionally, ulnar nerve mobility during elbow flexion and extension will be assessed. The nerve will be classified as stable if it remains within the cubital tunnel, subluxated if it moves to the level of the epicondyle, and dislocated if it shifts anterior to the medial epicondyle.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Hypermobility, Joint Joint Diseases Joint Instability Musculoskeletal Diseases

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Beylikdüzü State Hospital

Istanbul, Beylikdüzü, 34147, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged between 18 and 40 years
  • A Beighton score of 4 or higher (indicative of Generalized Joint Hypermobility)
  • Willingness to participate in the study

Exclusion criteria

  • Being under 18 or over 40 years of age
  • History of surgery or fracture in the elbow region
  • Presence of active infection at the measurement site
  • Presence of congenital anomaly in the upper extremity
  • History of surgery involving neural structures in the upper extremity
  • Presence of malignancy
  • Pregnancy
  • Presence of cognitive or psychiatric disorders

Treatment and study plan

No intervention

Other

no intervention

Primary outcomes

  1. Ulnar nerve cross-sectional area (CSA) at the medial epicondyle

    Time frame: 0 day

    CSA measurement provides insight into nerve thickening, which may indicate entrapment or irritation.

  2. Ulnar nerve cross-sectional area (CSA) at the 2 cm proximal of medial epicondyle

    Time frame: 0 day

    CSA measurement provides insight into nerve thickening, which may indicate entrapment or irritation.

  3. Ulnar nerve cross-sectional area (CSA) at the 2 cm distal of medial epicondyle

    Time frame: 0 day

    CSA measurement provides insight into nerve thickening, which may indicate entrapment or irritation.

  4. Ulnar nerve diameter

    Time frame: 0 day

    Ulnar nerve diameter with ultrasonography

  5. Ulnar nerve mobility classification during elbow flexion (stable/subluxated/dislocated)

    Time frame: 0 day

    Dynamic USG evaluation allows visualization of nerve movement and instability during joint motion.

Secondary outcomes

  1. Presence of ulnar nerve-related symptoms:

    Time frame: 0 day

    Symptom inquiry helps correlate clinical complaints with sonographic findings.

Sponsors and collaborators

Lead sponsor

Beylikduzu State Hospital

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 1, 2025
Registry last updated
Jul 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.