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Completed

NCT Number: NCT04780139

Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH.

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Key information

Age range

40 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ain Shams University hospital

Cairo, Cairo Governorate, Egypt

About this study

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH. Spinal anaesthesia is frequently used in daily clinical practice. Postspinal anaesthesia hypotension (PSAH) is a common side effect with an incidence of 15.3 to 33% that may result in organ hypoperfusion and ischaemic events. Patients' susceptibility to intraoperative hypotension can be influenced by the sensory block level, age, preoperative volume status , physical status, pre-operative medications and fasting.

PSAH due to spinal blockade is principally a consequence of diminished systemic vascular resistance after blockade of preganglionic sympathetic fibres. Many attempts have been tried to prevent PSAH, such as intravenous volume preload or prophylactic vasopressors. However, fluid infusion has been proved to lower the incidence of PSAH and significantly decrease vasopressor requirements. At the same time, empirical volume loading carries the potential of volume overload, particularly in patients with cardiac disease. Consequently, the search for predictors of PSAH is becoming mandatory to avoid blind volume loading and reserve it only for patients who are expected to develop PSAH. .

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients more than 40 years of age.
  • American Society of Anesthesiologists' (ASA) physical status 1 or 2.
  • scheduled for elective surgery under spinal anaesthesia in the supine position.

Exclusion criteria

  • BMI more than 35 kg m2.
  • taking angiotensin converting enzyme inhibitors.
  • pregnant women.
  • emergency cases.
  • absolute or relative contraindications to spinal anaesthesia.
  • Also, patients with a baseline arterial systolic blood pressure less than 90 mmHg or mean arterial blood pressure (MBP) less than 70 mmHg will be excluded.

Treatment and study plan

Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area

Diagnostic Test

Measuring the internal jugular vein cross section area and relate this to the incidence of hypotension after spinal anesthesia.

Primary outcomes

  1. Predictive value of internal jugular vein (IJV) cross sectional area.

    Time frame: 30 minutes

    The primary outcome is to evaluate the predictive value of internal jugular diameter cross sectional area for detecting PSAH

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension in Patients Undergoing Orthopedic Surgeries

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Mar 3, 2021
Registry last updated
Jul 23, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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