Ultrasonic Perfusion Imaging in Post-mastectomy Irradiated Patients

The purpose of this study is to evaluate post-mastectomy breast skin blood supply (perfusion) after radiation therapy, and before and after fat grafting to the breast(s).

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Key information

Conditions

Breast Reconstruction Dermatitis Fat Grafting Fibrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Radiation Dermatitis Radiation Fibrosis Radiation Fibrosis Syndrome Radiation Injuries Radiodermatitis Skin Diseases Skin and Connective Tissue Diseases Wounds and Injuries

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Breast cancer patients undergoing immediate tissue expander or implant reconstruction requiring radiation therapy
Have undergone mastectomy

Exclusion criteria

Patients who are unwilling to participate

Treatment and study plan

Fat Grafting

Procedure

Fat grafting

Primary outcomes

Radiation Fibrosis

Time frame: 12 months

Number of subject to experience radiation fibrosis

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Ultrasonic Perfusion Imaging for Monitoring Mastectomy Skin Microcirculation in Post-mastectomy Irradiated Patients Before and After Autologous Fat Transfer

Important dates

Study start: 2021
Primary completion: 2026
Study completion: 2026
First posted: Aug 5, 2021
Registry last updated: Jun 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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