UEMR Versus HSP in the Treatment of Pedunculated Colorectal Polyps Less Than 10mm in Size

• Patients are undergone screening, surveillance, or therapeutic colonoscopy at the Endoscopy department of Gastrointestinal endoscopy center of Huadong hospital affiliated to Fudan University.
• Randomize patients with pedunculated colorectal polyps less than 10mm in size into 2 interventional groups based on Random function of Statistical Package for the Social Sciences (SPSS) 20.0, including (1) Group 1: Underwater endoscopic mucosal resection (UEMR) and (2) Group 2: Hot snare polypectomy (HSP).
• Collecting variables which consist of primary and secodary outcomes.

Inclusion criteria

• Aged between 35 and 80 years
• Pedunculated colorectal polyps less than 10mm in size in screening, surveillance or therapeutic colonoscopy
• 0-Isp or 0-Ip according to Paris classification
• Patients must sign an informed consent form prior to registration in study

Exclusion criteria

• Unsuitable for removal by UEMR or HSP
• Suspected malignancy
• History of inflammatory bowel disease or colorectal resection
• Familial adenomatous polyposis or Lynch syndrome
• Patients taking anticoagulant and antiplatelet agents before the examination
• Inadequate bowel preparation, defined as a Boston Bowel Preparation Scale score < 6
• ASA >=3
• Pregnancy or breastfeeding
• Severe comorbid disease involving the heart, lungs, liver, or kidneys.
• Concurrent serious conditions, including other active malignancies or severe infectious diseases