Type 1 Diabetes Mellitus Effect on Bone Mineral Density

Because the diabetics are fracturing at a younger age than the general population (12), this leads us to believe there are significant factors that lead to fracture in Type 1 diabetes mellitus (DM) other than bone mineral density (BMD). Very little longitudinal data exists on BMD in adults with Type 1 DM and the effects of glucose control on BMD. No longitudinal data exists on pQCT in adults with Type 1 DM.

Hypothesis: Adult subjects with diabetes and poor glucose control will lose bone mineral density (BMD) as measured by DXA compared to age and sex matched healthy controls.

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Key information

Conditions

Diabetes Mellitus Bone Diseases Bone Diseases, Metabolic Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Musculoskeletal Diseases Nutritional and Metabolic Diseases Osteoporosis

Age range

19 year–50 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Creighton University

Omaha, Nebraska, 68131, United States

About this study

Because the diabetics are fracturing at a younger age than the general population(12), this leads us to believe there are significant factors that lead to fracture in Type 1 DM other than BMD. Very little longitudinal data exists on BMD in adults with Type 1 DM and the effects of glucose control on BMD. No longitudinal data exists on pQCT in adults with Type 1 DM.

Hypothesis: Adult subjects with diabetes and poor glucose control will lose bone mineral density (BMD) as measured by DXA compared to age and sex matched healthy controls.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

diabetic patients must have completed Visit 1 of the previous study.

Treatment and study plan

Primary outcomes

Bone mineral Density

Time frame: 5 years

Bone mineral density will be measured yearly for 5 years

Sponsors and collaborators

Lead sponsor

Creighton University

Other

Registry information

Official study title

Type 1 DM Effect on BMD: a Longitudinal Study in Adults

Important dates

Study start: 2012
Primary completion: 2014
Study completion: 2014
First posted: Jul 4, 2012
Registry last updated: Oct 31, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed