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Enrolling by Invitation

NCT Number: NCT06108531

Tumor Exosome Liquid Biopsy Strategy to Diagnose Pancreatic Cancer

This is an observational study of patients diagnosed with pancreatic cancer by pathology, with a control group of patients with pathology suggestive of benign pancreatic lesions and normal subjects, and the diagnostic ability of exosomes to identify patients with pancreatic cancer was assessed through the detection of exosomes in the peripheral blood.

Enrolling by Invitation

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Key information

Conditions

Pancreatic

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine

Shanghai, Shanghai Municipality, 20092, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosis of pancreatic cancer confirmed by imaging (case) Diagnosis of chronic pancreatitis confirmed by imaging (hospital control)

Exclusion criteria

The pathology diagnosis and imaging does not matched Patients with other malignant tumors Patients with other severe systemic diseases

Treatment and study plan

Primary outcomes

  1. Characterization of proteins in tumor exosomes from patients with pancreatic cancer

    Time frame: Up to 2 years from start of study

    We will select specific protein A from circulating exosomes of pancreatic cancer patients for further analysis.

  2. The expression of protein A in the circulating exosomes from patients

    Time frame: Up to 2 years from start of study

    By detecting the expression of protein A in circulating exosomes of patients. the ROC curve of A+ circulating exosomes will be compared to clinical standard tumor biomarkers (e.g., CA199) in pancreatic cancer patients.

Sponsors and collaborators

Lead sponsor

Shanghai Jiao Tong University School of Medicine

Other

Registry information

Official study title

Study on the Application of Tumor Exosome Liquid Biopsy in the Early Diagnosis of Pancreatic Cancer

Important dates

Study start
2023
Primary completion
2025
Study completion
2026
First posted
Oct 31, 2023
Registry last updated
Oct 31, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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