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Completed

NCT Number: NCT00000324

Tryptophan and Behavior Therapy for Cocaine Abuse - 1

The purpose of this study is to assess the efficacy of tryptophan vs. placebo, and voucher payments vs. a control condition, in the treatment of cocaine dependence.

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Key information

Conditions

Cocaine-Related Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Johns Hopkins University School of Medicine

Baltimore, Maryland, 21224, United States

About this study

This clinical trial uses a 2 by 2 design to compare tryptophan to placebo, and voucher incentives vs. a control condition, in the outpatient treatment of cocaine dependence- using a relapse prevention model of treatment intervention.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Cocaine dependent

Exclusion criteria

  • Physically dependent on drugs of abuse other than cocaine
  • Significant medical or psychiatric illness (besides substance abuse disorder)
  • Pregnant

Treatment and study plan

Tryptophan

Drug

Primary outcomes

  1. Side effects

  2. Retention

  3. Cocaine use

  4. Cocaine craving

  5. Other drug use

  6. Psychosocial functioning

Sponsors and collaborators

Lead sponsor

National Institute on Drug Abuse (NIDA)

Nih

Collaborators

  • Johns Hopkins University

Registry information

Official study title

Tryptophan and Behavior Therapy for Cocaine Abuse

Important dates

Study start
1997
Study completion
2001
First posted
Sep 21, 1999
Registry last updated
Jan 12, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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