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NCT Number: NCT04804930

Trichoscopy and Systemic Scleroderma

* Few data are available on scalp involvement in systemic scleroderma. * Few data are available on the association between scalp abnormalities and features of systemic scleroderma * Trichoscopy is a simple, reproducible, noninvasive examination that is part of the examination of hairy areas in routine dermatologic practice * There is a lack of simple, noninvasive examinations to evaluate patients with systemic scleroderma

The objective will be to evaluate the contribution of trichoscopy in the evaluation of patients with systemic scleroderma

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Key information

Conditions

Scleroderma, Systemic Connective Tissue Diseases Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hop Claude Huriez Chu Lille

Lille, 59037, France

Location status: Recruiting

Location contact

Vincent Sobansky, MD

PRINCIPAL_INVESTIGATOR

CONTACT

0320445962

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient who fulfils the Systemic scleroderma ACR-EULAR 2013 criteria
  • Signed informed consent
  • Being social insured

Exclusion criteria

  • Patients aged less than 18 years old
  • patients under legal protection
  • patients deprived of their liberty
  • patients in emergency situations
  • patients who refused or unable to give informed consent
  • For the control group: sclap inflammatory disease active the day of the examination

Treatment and study plan

picture

Procedure

We will perform a non-invasive assessment of the scalp with a dermoscope by taking two standardized pictures on the frontal area and the occipital area in order to a blinded analysis of trichoscopic patterns

Other names: Non-invasive trichoscopy: dermoscopic assessment of the scalp (picture)

Primary outcomes

  1. Frequency of elementary lesions observed by trichoscopic assessment of the scalp

    Time frame: Baseline

    Comparison of the frequencies of elementary lesions visualized in patients with systemic scleroderma and healthy subjects

Secondary outcomes

  1. Correlation between visceral damage of systemic scleroderma and trichoscopic features

    Time frame: Baseline

    Frequency of visceral damage of systemic scleroderma: pulmonary hypertension, lung fibrosis, kidney failure.

  2. Correlation between global severity of systemic scleroderma and trichoscopic features

    Time frame: Baseline

    Correlation between EUSTAR score, Rodnan score, Medsger's score and trichoscopic features

  3. Correlation between autoimmune profile of sclerodermic patients and trichoscopic features

    Time frame: Baseline

    Correlation of antibodies, inflammatory profile of patients with trichoscopic features.

Study contacts

Contact information is provided by the study sponsor or research team.

Vincent Sobanski, MD

CONTACT

[email protected]

0320445962

Sponsors and collaborators

Lead sponsor

University Hospital, Lille

Other

Registry information

Official study title

Prognostic Value of Trichoscopy in Patients With Systemic Scleroderma

Acronym: TRICHLOSCLERO

Important dates

Study start
2021
Primary completion
2026
Study completion
2026
First posted
Mar 18, 2021
Registry last updated
Apr 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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