Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07042061

Trial of Mobile External Defibrillator for Out-of-hospital Cardiac Arrest in Singapore.

The goal of this clinical trial is to learn the feasibility of equipping the volunteer community responders (VCR) with the mobile external automated defibrillators (mAEDs) for the management of adults experiencing out-of-hospital cardiac arrest (OHCA) patients. It will also provide early signals if this enhanced system can help increase the frequency of defibrillation and doing it earlier. The main questions it aims to answer are:

* Can equipped VCRs apply mAEDs more frequently and earlier to potentially get more patients successfully resuscitated? * Is this system enhancement is feasible in the long run.

Participants, the VCRs, will:

* Carry a 450 gm mAED with them all the time for up to an year and use it on an OHCA patient if and when alerted to help. * They will hand over this single-use battery-operated device to the EMS crew for data retrieval and potential replacement * They will be interviewed for their experience of being equipped and use of the mAED.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Out-Of-Hospital Cardiac Arrest (OHCA) Cardiovascular Diseases Heart Arrest Heart Diseases Out-of-Hospital Cardiac Arrest

Age range

21 year–74 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

1.1. Inclusion Criteria

Study participants must meet all the inclusion criteria to participate in this study:

  • Must be proficient in English. Able to read and understand English fluently.
  • Be aged 21-74 years of age at point of recruitment.
  • Willing and able to move rapidly to a scene that can be 400 meters away from their location.
  • Be a registered CFR with SCDF.
  • Must be active myResponder® mobile phone app user so they can receive alerts about nearby OHCA cases.

1.2. Exclusion Criteria All subjects meeting any of the following exclusion criteria will be excluded from participation in this study.

  • Not proficient in English. Cannot read and understand English.
  • Aged less than 21 and over 74 years of age.
  • Not willing to be a myResponder app user.
  • Not able to move rapidly to a scene that can be 400 meters away from their location.
  • Given the short duration of the trial, those who are pregnant will be ineligible.
  • Those experiencing any serious physical injury or handicap and those with obvious mental handicap.

Treatment and study plan

Mobile external automated defibrillator

Device

A single-use, hand-held, chocolate bar sized portable AED

Primary outcomes

  1. Feasibility of a full scale trial

    Time frame: Through study completion, an average of 1 year

    A validated AIM/FIM tool will be used to collect perceptions of the users and managers using a likert scale measurement reporting on feasibility and acceptability of the intervention

Secondary outcomes

  1. Qualitative experiences of CFR elicited through semi-structured interviews

    Time frame: 1 year

    Experience of the CFRs as regards challenges faced while carrying the device and convenience when the device is needed

  2. Qualitative experiences of CFR elicited through semi-structured interviews

    Time frame: 1 year

    Experience of the CFRs as regards challenges of using the new device as compared to standard of care device

  3. Qualitative experiences of CFR elicited through semi-structured interviews

    Time frame: 1 year

    Responses of the patient's relatives regarding the use of the device by CFRs before and after the usage as perceived by the CFRs

Other outcomes

  1. Exploratory outcome mesaures

    Time frame: 1 year

    Acceptability of the volunteers to carry it for 24 months (# of acceptors/# offered to carry; proportion, presented in %)

  2. Exploratory outcome mesaures

    Time frame: 1 year

    Convenience to carry for an extended duration (# stopped carrying/#acceptors; proportion, presented in %)

  3. Exploratory outcome mesaures

    Time frame: 1 year

    Availability when needed (# of carrying the device when needed/# acceptors; proportion, presented in %)

Study contacts

Contact information is provided by the study sponsor or research team.

Fahad J Siddiqui

CONTACT

[email protected]

+65 66017951

Garion Senior Executive

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Singapore General Hospital

Other

Collaborators

  • Duke-NUS Graduate Medical School
  • Singapore Civil Defence Force

Registry information

Official study title

Out-of-Hospital Cardiac Arrest Care Through Empowered and Equipped Community First Responders: Mobile External Defibrillation Investigation for Cardiac Arrest in Singapore (MEDICS).

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Jun 27, 2025
Registry last updated
Apr 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.