Trial of Cognitive Behavioral Therapy to Reduce Antiretroviral Therapy Side Effects

HIV patients on antiretroviral medications, who are suffering from pain, nausea, anxiety, or fatigue will be randomly assigned to either the usual care for an HIV patient, which is an educational program about the medications, or an intervention program, which includes both the educational program and three sessions with a psychologist. The sessions will help participants understand their concerns about the medications and will teach relaxation techniques and guided imagery to help participants reduce discomforts associated with the medications. All patients will continue to receive the usual care from their medical providers. The main measures are the measured frequency and intensity of the symptoms under study; secondary measures examine medication adherence, CD4 counts, and virus levels. Control measures include the number of doses of side effect medications taken in each group, and the number of relaxation/imagery sessions practiced privately by participants in the intervention group.

Inclusion criteria

• Participants currently taking antiretroviral medications for HIV
• Participants suffer from one or more: nausea, pain, fatigue, anxiety

Exclusion criteria

• Non-English speaking/reading
• Pregnant or planning to become pregnant within 3 months
• Any severe health problem that would prevent participation (e.g., opportunistic infection requiring hospitalization)
• Substance abuse preventing active participation in care