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Completed

NCT Number: NCT00000359

Treatments for Benign Paroxysmal Positional Vertigo (BPPV)

The purpose of this study was to determine the relative short- and long-term efficacy of several physical treatment paradigms commonly employed for the treatment of benign paroxysmal positional vertigo (BPPV), including the canalith repositioning (Epley) maneuver, the liberatory (Semont) maneuver, the Brandt-Daroff exercises and nonspecific vestibular habituation exercises. These procedures involve exercises and head manipulations. Vertigo intensity and frequency, the presence/absence of slow-phase eye movements, the degree of dizziness handicap and acts of daily living (ADL) were assessed. The study also ascertained the effects of co-morbid conditions on the response to treatment. While BPPV is a common and significant public health problem that has been recognized for several decades, this is the first systematic study of the relative treatment efficacy of different physical treatment modalities for this disorder.

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Key information

Conditions

Vertigo Ear Diseases Labyrinth Diseases Nervous System Diseases Neurologic Manifestations Otorhinolaryngologic Diseases Pathological Conditions, Signs and Symptoms Signs and Symptoms Vestibular Diseases

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Baylor College of Medicine

Houston, Texas, 77030, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients may be eligible for this study if they:

  • Are at least 21 years old.
  • Have a diagnosis of unilateral posterior semicircular canal BPPV according to established clinical test criteria.
  • Have functional to normal range of motion of the neck and the back.

Exclusion criteria

Patients will not be eligible for this study if they:

  • Have a history of prior ear surgery or prior treatment for BPPV.
  • Have an orthopedic or connective tissue disorder that impairs functional neck or trunk range of motion.
  • Have a significant neurological disorder or spinal cord damage.
  • Are on vestibular suppressant medications.
  • Have Meniere's disease or acoustic neuromas.

Treatment and study plan

Canalith repositioning maneuver (Epley maneuver)

Behavioral

Standard passive motion of the head: Dix-Hallpike maneuver, turn head to opposite side, roll over, sit up.

Other names: CRP, Epley maneuver

Semont maneuver

Behavioral

Sidelying maneuver, flip over 180 deg, sit up.

Other names: Liberatory maneuver

Brandt-Daroff Exercises

Behavioral

Active exercise. Sidelying to involved side, sidelying to uninvolved side, sit up.

Vestibular habituation exercises

Behavioral

Head shaking exercises in pitch, roll, yaw and circumduction. Titrating from 2 repetitions per exercise to 20 repetitions per exercise, as tolerated.

ShamManeuver

Behavioral

Passive movement of the head

Primary outcomes

  1. Vertigo

    Time frame: 6 month s

Secondary outcomes

  1. Balance

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Baylor College of Medicine

Other

Collaborators

  • National Institute on Deafness and Other Communication Disorders (NIDCD)

Registry information

Important dates

Study start
1998
Primary completion
2003
Study completion
2003
First posted
Nov 3, 1999
Registry last updated
Jul 26, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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