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OpenTrials
Completed

NCT Number: NCT00812188

Treatment Study Comparing Medium or High Dose Uva-1 Treatment 3x/Week Versus Fluocinonide 0.05% Cream in the Treatment of Morphea.

Compare UVA-1 phototherapy treatment to topical steroid treatment in subjects with morphea.

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Key information

Conditions

Symmetric Limited Morphea Connective Tissue Diseases Scleroderma, Localized Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UT Southwestern Medical Center at Dallas - Department of Dermatology Clinical Trials

Dallas, Texas, 75390, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male and female subjects 18 years of age or older.
  • Symmetric limited morphea.

Exclusion criteria

  • Known sensitivity to fluocinonide 0.05% cream.
  • Clinical evidence of superinfected skin.
  • Immunocompromised state (including previously documented HIV).
  • Generalized Scleroderma.
  • Previous history of skin cancer.
  • Non-English speaking subjects.

Treatment and study plan

Medium Dose UVA-1

Other

UVA-1 phototherapy treatment (60 J/cm2) three times per week for 12 weeks.

High Dose UVA-1

Other

High dose (120 J/cm2)UVA-1 phototherapy three times per week for 12 weeks.

Primary outcomes

  1. Efficacy of UVA-1 treatment vs. topical steroid.

    Time frame: 5 years

Sponsors and collaborators

Lead sponsor

University of Texas Southwestern Medical Center

Other

Registry information

Official study title

A Prospective, Open Label Trial of High Dose UVA-1, 3x/Week or Medium Dose UVA-1, 3x/Week vs. Fluocinonide 0.05% Cream Treatment of Morphea

Important dates

Study start
2004
Primary completion
2009
Study completion
2009
First posted
Dec 22, 2008
Registry last updated
Feb 18, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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