Skip to main content
OpenTrials
Completed

NCT Number: NCT07031466

Treatment Outcome in Patients After eCPR

This study consists of two parts - retrospective and prospective. The aim of this study is to assess the quality of life in bio-psycho-social dimensions in patients after eCPR (extracorporeal cardiopulmonary resuscitation), in relation to their neurological outcome after the end of treatment and discharge from the Ostrava University Hospital (FNO). The study will focus on patients who underwent extracorporeal membrane oxygenation (ECMO) support after out-of-hospital cardiac arrest (OHCA) in the years 2022-2024.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Ostrava, Ostrava, Moravian-Silesian Region, Czechia

Loading trial locations.

About this study

Retrospective study Quantitative evaluation using data analysis from documentation. Patients on ECMO after OHCA in the period 1. 1. 2022 - 31. 12. 2024 will be evaluated based on data from the documentation. Analysis of data from the documentation of selected patients will be performed, evaluating demographic data, comorbidities, duration of ECMO support, mortality, Cerebral Performance Category (CPC) score 30 days after CPR.

Prospective study Quantitative assessment using validated questionnaire tools Patients connected to ECMO after OHCA in the period 1. 1. 2022 - 31. 12. 2024, in whom a CPC score >3 was detected after the 30th day from cardiac arrest and who were discharged from the FNO. As part of patient dispensary, these patients are electively invited to the PICS outpatient clinic in the FNO Ostrava. Individual interviews (filling out questionnaires) will be performed after obtaining informed consent in the Post-Intensive Care Syndrome (PICS) outpatient clinic at the University Hospital Ostrava, or telephone interviews conducted by the attending physician.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient who underwent eCPR after OHCA at University Hospital Ostrava
  • Hospitalised in the period from 1. 1. 2022 to 31. 12. 2024
  • Ability to undergo an interview personally or a family member able to provide information
  • Signed informed consent

Exclusion criteria

  • Language barrier
  • Acute serious mental or somatic disease making the interview not feasible

Treatment and study plan

Retrospective analysis of assigned treatment

Other

Retrospective analysis of assigned treatment will be performed

Quality of Life (SF-36)

Other

The quality of life will be assessed using the SF-36 (Short-Form Health Subject Questionnaire).

Quality of Life (EQ-5D)

Other

The quality of life will be assessed using the EQ-5D (European Quality of Life Questionnaire)

Hospital Anxiety and Depression (HADS)

Other

Hospital Anxiety and Depression will be assessed using the HADS (Hospital Anxiety and Depression Scale)

Primary outcomes

  1. Quality of Life (SF-36)

    Time frame: 30 days

    Quality of Life in patients after eCPR will be assessed using the SF-36 questionnaire 30 days after eCPR

  2. Quality of Life (EQ-5D)

    Time frame: 30 days

    Quality of Life in patients after eCPR will be assessed using the EQ-5D questionnaire 30 days after eCPR

  3. Hospital Anxiety and Depression Scale (HADS)

    Time frame: 30 days

    Hospital Anxiety and Depression Scale (HADS) in patients after eCPR will be assessed using the EQ-5D questionnaire 30 days after eCPR

Sponsors and collaborators

Lead sponsor

University Hospital Ostrava

Other

Registry information

Important dates

Study start
2022
Primary completion
2025
Study completion
2025
First posted
Jun 22, 2025
Registry last updated
Dec 5, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.