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NCT Number: NCT07728357

Treatment of Pectoralis Trigger Points in Patients With Pseudo Angina

Pseudo-angina is a musculoskeletal condition characterized by chest pain that resembles angina but occurs due to non-cardiac causes, particularly myofascial trigger points in the chest wall muscles. Trigger points in the pectoralis major and minor muscles may contribute to pain, discomfort, and functional limitations by affecting muscle activity and movement. Manual therapy techniques such as the Graston Technique and Local Ischemic Compression (LIC) are commonly used to manage soft tissue dysfunction and myofascial trigger points. This study aims to compare the effects of the Graston Technique and Local Ischemic Compression on pain reduction and functional improvement in patients with pseudo-angina.

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Key information

Conditions

Pseudo Angina Chest Pain Muscular Diseases Musculoskeletal Chest Pain Musculoskeletal Diseases Myofascial Pain Syndromes Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Pectoralis Muscles Signs and Symptoms

Age range

25 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The University of Faisalabad

Faisalābad, Punjab Province, 38000, Pakistan

About this study

This is Multiple-center, randomized controlled trail. Participants age 25-50 years with diagnosed pseudo angina will be referred from cardiology department of Aziz Fatima and Faisal hospital to Madina Teaching hospital (MTH) Physiotherapy ward and Jafar Physiotherapy Clinic. After informed consent Participants will be randomly assign to one of two parallel groups using a random number generator. Group A (Experimental): Receive Graston technique 3 sessions per week for total duration 4 weeks. Group B (Active Comparator) receive the LIC 3 sessions per week for total duration 4 weeks. Outcome measures (pain via NPRS, Shoulder Pain and Disability Index (SPADI)) are taken at baseline and end of treatment. Data will be analyzed using Spss version 20.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants which fulfill the Simon's Trigger Point Diagnostic Criteria
  • Referred by Cardiologist • Patients with Trigger Points in chest Muscles and left Pectoralis Major and Minor muscles.

Exclusion criteria

  • Spinal Deformity • Gastric Problems • Any cardiac disease • Heart Burns • Panic Attacks • Pleurisy • Pulmonary Embolism • Pericarditis.

Treatment and study plan

Graston Technique

Other

A stainless-steel Graston instrument was applied using controlled strokes at approximately a 45° angle to the skin surface, following the direction of the muscle fibers and across the fibers to mobilize soft tissue restrictions. The treatment was applied for approximately 40-120 seconds over each targeted area.

Local Ischemic Compression

Other

Sustained manual pressure was applied gradually over each trigger point until a tolerable level of discomfort was achieved. The compression was maintained for approximately 90 seconds per trigger point and repeated 1-3 times during each treatment session according to patient tolerance and clinical response. The technique was performed using the therapist's thumb, finger, or knuckle depending on the location and depth of the trigger point

Primary outcomes

  1. Shoulder Pain Disability Index

    Time frame: Baseline and 4 week post intervention

    The Shoulder Pain and Disability Index is a well-known neutral measure for assessing the level of pain and functional impairment experienced by people with shoulder issues. It is frequently used in clinical and research settings to assess the severity of shoulder problems and track therapy efficacy. It consists of 13 elements organized into two subscales. The Pain Subscale consists of five items that determine how intense pain is in various circumstances, such as at rest or during activities. The disability subscale consists of eight items: it assesses the level of difficulty with specific everyday shoulder-related tasks, such as lifting weights or putting on a shir

  2. Numeric Pain Rating Scale

    Time frame: Baseline and 4 week post intervention

    NPRS was used as a primary outcome measure to evaluate pain intensity in patients with pseudo-angina. On the scale, 0 represents no discomfort and 10 represents severe pain. At rest and while engaging in activities, participants were asked to rate their level of pain.

Study contacts

Contact information is provided by the study sponsor or research team.

Dr Maryam Farooq, Phd Physical therapy

CONTACT

[email protected]

+923326760155

Dr. Muhammad Muneeb Jafar, PhD Physical therapy

CONTACT

[email protected]

+923127000616

Sponsors and collaborators

Lead sponsor

University of Faisalabad

Other

Registry information

Official study title

Comparative Effects of Graston Technique Versus Local Ischemic Compression on Trigger Points of Pectoralis Major and Minor Among Pseudo-angina Patients

Acronym: GT-LIC

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 27, 2026
Registry last updated
Jul 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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