Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, 100000, China
Location status: Recruiting
Recruiting
NCT Number: NCT05388682
Treatment of Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement
1. Evaluate the effect of medical treatment and percutaneous transluminal pulmonary angioplasty on takayasu arteritis with pulmonary artery involvement 2. evaluate the efficacy of FAPI in predicting the activity and treatment efficacy of takayasu arteritis with pulmonary artery involvement
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
At baseline, FAPI and FDG are performed to evaluate the activity of takayasu arteritis with pulmonary artery involvement. FAPI is also used to predict the treatment efficacy and prognosis of takayasu arteritis with pulmonary artery involvement.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- patients diagnosed with Takayasu arteries with pulmonary arteries involvement
Exclusion criteria
- Patients had pulmonary artery stenosis arising from CTEPH, fibrosing mediastinitis and congenital pulmonary artery stenosis
Treatment and study plan
Percutaneous transluminal pulmonary angioplasty
DevicePercutaneous transluminal pulmonary angioplasty
Primary outcomes
-
all cause death
Time frame: 2014/1/1-2042/12/31
all cause death
-
mean pulmonary arterial pressure change
Time frame: 2014/1/1-2042/12/31
change of mean pulmonary arterial pressure after treatment
-
pulmonary vascular resistance change
Time frame: 2014/1/1-2042/12/31
chagne of pulmonary vascular resistance after treatment
-
6MWD change
Time frame: 2014/1/1-2042/12/31
change of six minute walk distance after treatment
-
peak VO2 change
Time frame: 2014/1/1-2042/12/31
change of peak oxygen consumption after treatment
-
NT-proBNP change
Time frame: 2014/1/1-2042/12/31
change of NT-proBNP after treatment
-
RV/LV change
Time frame: 2014/1/1-2042/12/31
change of right ventricular end-diastolic diameter versus laboratory left ventricular end-diastolic diameterafter treatment
-
CI change
Time frame: 2014/1/1-2042/12/31
change of cardiac index after treatment
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
Chinese Pulmonary Vascular Disease Research Group
Other
Registry information
Official study title
Observation of Long Term Effect of Medical and PTPA Treatment on Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement
Important dates
- Study start
- 2014
- Primary completion
- 2042
- Study completion
- 2042
- First posted
- May 24, 2022
- Registry last updated
- Dec 20, 2023
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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