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OpenTrials
Completed

NCT Number: NCT05993286

Treatment of Misophonia: Comparison of Exposure and Sound Therapy

The goal of this clinical trial is to compare the effects of possible treatments in misophonics. The main question it aims to answer is:

- Is exposure more effective on misophonic symptoms than sound therapy? Participants are randomly assinged to three groups of treatment;

1. Psychoeducation 2. Psychoeducation + Exposure 3. Psychoeducation + Sound Therapy

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Key information

Conditions

Misophonia

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hacettepe University Department of Psychiatry

Ankara, 06000, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • People have Misophonia

Exclusion criteria

  • Current psychosis
  • Mental retardation or dementia
  • those who had previously received exposure or sound therapy for misophonia symptoms.

Treatment and study plan

Exposure Therapy

Behavioral

At Week 0, the homework was to expose oneself to these sounds for 20 minutes a day, three days a week for three weeks.

At the Week 3 interview, the frequency and severity of the homework were adjusted based on the degree of improvement in the symptoms and the person's adherence to the instructions.

Sound Therapy

Other

Participants were asked to listen to specifically modulated music for twenty minutes a day, three days a week, for the first three weeks. At the Week 3 assessment, if the patient reported no or little benefit in their misophonia symptoms, the instruction was modified (intensified) to listening to the same music for forty minutes a day, three days a week.

Psychoeducation

Other

A psychoeducation session, prepared by the research team was delivered by the investigator to each patient at the study intake.

Primary outcomes

  1. The mean change in Misophonia Total Score (MTS)

    Time frame: Week 0 and Week 6

    The difference between MTS Week 0 and MTS Week 6 was calculated, divided by MTS Week 0, and multiplied by 100, to elicit the percent change in MTS between Week 0 and Week 6.

  2. The "improvement"

    Time frame: Week 3 and Week 6

    It was rated by the investigator (KBA) based on her clinical judgement (0=some worsening, 1=no improvement, 2=some improvement, 3=moderate improvement, 4=much improvement). If there was a moderate to much improvement at any point, the case was rated as "improved"; and "not improved" if the score was little worsening, no improvement, or some improvement.

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Important dates

Study start
2019
Primary completion
2021
Study completion
2021
First posted
Aug 15, 2023
Registry last updated
Aug 15, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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