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NCT Number: NCT01366430

Treatment of Geotropic Horizontal Canal Benign Paroxysmal Positional Vertigo

The purpose of this study was to compare the immediate efficacies of each treatment maneuvers in treatment of geotorpic horizontal canal benign paroxysmal positional vertigo (HC-BPPV).

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Key information

Conditions

Benign Paroxysmal Positional Vertigo Cranial Nerve Diseases Ear Diseases Eye Diseases Labyrinth Diseases Nervous System Diseases Neurologic Manifestations Nystagmus, Pathologic Ocular Motility Disorders Otorhinolaryngologic Diseases Pathological Conditions, Signs and Symptoms Signs and Symptoms Vertigo Vestibular Diseases

Age range

11 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Chonbuk National University Hospital, Jeonju, Cholabuk-do, South Korea

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About this study

A randomized prospective study of patients with HC-BPPV. Patients with geotropic type of HC-BPPV were randomized to one of each three treatment groups at their first clinic visit. These groups included the barbecue maneuver, Gufoni's maneuver, and sham group in geotropic HC-BPPV. Responsiveness of treatment maneuver was determined by positioning maneuver immediately after each treatment method based on resolves of vertigo and positional nystagmus.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • a history of brief episodes of positional vertigo, direction-changing horizontal nystagmus beating toward the uppermost (apogeotropic nystagmus) ear in both the lateral head turning positions,
  • no spontaneous nystagmus during upright sitting position
  • absence of identifiable central nervous system disorders that could explain the positional vertigo and nystagmus

Exclusion criteria

  • central positional nystagmus with identifiable CNS lesions that could explain the positional nystagmus

Treatment and study plan

Gufoni

Procedure

For Gufoni maneuver, the patient was quickly brought down on the healthy side from the sitting position, and the head was then turned about 45 degree down, so that the nose was on the bed. After 2 minutes in this position, the patient was returned to the upright position.

Sham

Procedure

The sham maneuver the opposite of the first step for barbecue rotation; lying down from sitting position for 30 seconds, and head turn 90degree to the affected side for 1 minute, and then sit up.

Barbecue

Procedure

For barbecue rotation, the head was rotated rapidly 90degree while supine in the direction of the healthy ear, which was immediately followed by a truncal rotation of 90degree in the same direction to lie on the intact side. After 30-60 seconds when the induced nystagmus was dissipated, the patients were subjected to a further 90degree rotation of the head and trunk en block in the same direction to attain the nose-down position. After a further 30-60 seconds, the head was again turned in the same direction so that the affected ear was downward. Finally, after another 30-60s, the patient was brought to sitting position. Only one maneuver was performed per session.

Primary outcomes

  1. Immediate therapeutic effects for the treatment of geotropic HC-BPPV

    Time frame: one hour

    The immediate treatment response was determined by participating neurologists in each clinic without knowing the maneuver applied to each patient from 30 minutes to one hour after initial maneuver. The absence of both vertigo and nystagmus was required to determine a resolution. When the patient still showed positioning nystagmus or vertigo, the patient received the previously applied maneuver again.

Sponsors and collaborators

Lead sponsor

Chonbuk National University

Other

Collaborators

  • Seoul National University Bundang Hospital

Registry information

Official study title

Treatment of Geotropic Horizontal Canal Benign Paroxysmal Positional Vertigo; Randomized Controlled Trial of Barbeque Rotation and Gufoni Maneuver

Acronym: HC BPPV

Important dates

Study start
2009
Primary completion
2011
Study completion
2011
First posted
Jun 6, 2011
Registry last updated
Jun 6, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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