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Completed

NCT Number: NCT02046980

Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo

To determine the short term therapeutic efficacies of Gufoni maneuver and mastoid oscillation in apogeotropic type of benign paroxysmal positional vertigo (BPPV) involving the horizontal semicircular canal (HC-BPPV), a randomized, prospective, sham-controlled study was conducted.

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Key information

Age range

19 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Daegu Kyungbook Dizziness society

Daegu, South Korea

About this study

The apogeotropic type of benign paroxysmal positional vertigo involving the horizontal canal (HC-BPPV) is likely due to otolithic debris in the anterior arm of the canal (canalithiasis) or the debris attached to the cupula (cupulolithiasis). It is important to seek the method to convert treatment-resistant apogeotropic form to the more treatment-responsive geotropic form in HC-BPPV. Recent randomized trials demonstrated that head shaking maneuver was more effective than the modified Semont maneuver and the Gufoni and head shaking maneuvers showed similar efficacy in treating apogeotropic HC-BPPV. Moreover, new repositioning maneuver using mastoid vibration showed good efficacies in patients with apogeotropic HC-BPPV in recent study. So we tried to compare the short term therapeutic efficacies of Gufoni maneuver and mastoid oscillation in apogeotropic HC-BPPV with a randomized, prospective, sham-controlled study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • history of vertigo associated with changes in head position
  • direction-changing horizontal nystagmus beating toward the uppermost ear (apogeotropic nystagmus) in both turning positions detected with Frenzel glasses or videoculography in the Head turning test
  • vertigo associated with the elicited nystagmus
  • symptom within 2 weeks
  • put one's signature on consent

Exclusion criteria

  • patients with identifiable central nervous system disorders that could explain the positional vertigo and nystagmus
  • the patients with apogeotropic form which was transited from geotropic after previous therapeutic maneuvers
  • the patients who transited from apogeotropic from vertical canal BPPV during study
  • patients who had possible cause of secondary BPPV such as Meniere's disease, migraine or recent trauma history
  • patients whose affected ear cannot be identified
  • patients with multiple canal atypical positional nystagmus or who were treated previously with repositioning maneuvers were excluded.
  • patients with cervical or lumbar spine problem

Treatment and study plan

Gufoni

Procedure

vibration

Procedure

Sham

Procedure

Primary outcomes

  1. Conversion in Direction of Nystagmus From Apogeotropic to Geotropic or Disappearance of Nystagmus

    Time frame: 2 days

Sponsors and collaborators

Lead sponsor

Keimyung University Dongsan Medical Center

Other

Registry information

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Jan 28, 2014
Registry last updated
Mar 11, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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