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OpenTrials
Completed

NCT Number: NCT02260167

Treatment of Alzheimer's and Dementia With the Metabolism, Infections, Nutrition, Drug Elimination (MIND) Protocol

Treating with measures that may improve metabolic functioning of neurons in an integrated protocol

Completed

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

PAN

Kailua, Hawaii, 96740, United States

About this study

Most organ failure results in modest drops in function until over 50% of function is lost. At a certain point, even modest drops in physiologic activity result in dramatic drops in clinical function. Though less homogeneous than in other organs, clinical experience and the literature suggests a similar process occurs in the brain. The hypothesis is that by using an integrated protocol to, essentially, "tune up" neuronal function, a 5-10 % improvement in metabolic functioning may translate to significant improvement in clinical functioning. This tune-up will include "MIND":

M- Metabolism-- optimizing hormonal function I- Infections-- looking for and eliminating N- Nutritional and herbal support D- Drugs- Weaning subjects off unneeded medications

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • A diagnosis of Alzheimer's and/or dementia with an MMSE score over 12 or being ambulatory and able to travel outside the home with assistance.
  • Must have a caregiver living with them.

Exclusion criteria

  • Overt progressive and severe causes of secondary dementia such as metastatic brain cancers, or severe overt infectious encephalopathies or severe autoimmune illness.
  • Also, severe life threatening illnesses which would make them unlikely to be alive after 6-12 months

Treatment and study plan

A mix of natural treatments and medications

Other

Other names: MIND Protocol

Primary outcomes

  1. Montreal Cognitive Assessment (MoCA)

    Time frame: 6 months

    Looking to see what percent of patients show improvement

Secondary outcomes

  1. Mini Mental Status Exam (MMSE)

    Time frame: 6 months

  2. Alzheimer's Disease Assessment Scale- Activities of Daily Living (ADAS-ADL)

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Practitioners Alliance Network

Other

Registry information

Official study title

Effective Treatment of Alzheimer's and Dementia With the MIND Protocol

Acronym: MIND

Important dates

Study start
2014
Primary completion
2017
Study completion
2017
First posted
Oct 9, 2014
Registry last updated
May 8, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.